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Int. J. Environ. Res. Public Health 2018, 15(10), 2217;

Association Between PM2.5 and Daily Hospital Admissions for Heart Failure: A Time-Series Analysis in Beijing

School of Public Health, Peking University, Beijing 100191, China
Peking University Medical Informatics Center, Beijing 100191, China
Author to whom correspondence should be addressed.
Received: 10 September 2018 / Revised: 29 September 2018 / Accepted: 7 October 2018 / Published: 11 October 2018
PDF [469 KB, uploaded 11 October 2018]


There is little evidence that acute exposure to fine particulate matter (PM2.5) impacts the rate of hospitalization for congestive heart failure (CHF) in developing countries. The primary purpose of the present retrospective study was to evaluate the short-term association between ambient PM2.5 and hospitalization for CHF in Beijing, China. A total of 15,256 hospital admissions for CHF from January 2010 to June 2012 were identified from Beijing Medical Claim Data for Employees and a time-series design with generalized additive Poisson model was used to assess the obtained data. We found a clear significant exposure response association between PM2.5 and the number of hospitalizations for CHF. Increasing PM2.5 daily concentrations by 10 μg/m3 caused a 0.35% (95% CI, 0.06–0.64%) increase in the number of CHF admissions on the same day. We also found that female and older patients were more susceptible to PM2.5. These associations remained significant in sensitivity analyses involving changing the degrees of freedom of calendar time, temperature, and relative humidity. PM2.5 was associated with significantly increased risk of hospitalization for CHF in this citywide study. These findings may contribute to the limited scientific evidence about the acute impacts of PM2.5 on CHF in China. View Full-Text
Keywords: air pollution; PM2.5; heart failure; short-term association air pollution; PM2.5; heart failure; short-term association

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Li, M.; Wu, Y.; Tian, Y.-H.; Cao, Y.-Y.; Song, J.; Huang, Z.; Wang, X.-W.; Hu, Y.-H. Association Between PM2.5 and Daily Hospital Admissions for Heart Failure: A Time-Series Analysis in Beijing. Int. J. Environ. Res. Public Health 2018, 15, 2217.

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