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Open AccessCase Report

Unusual Onset of Celiac Disease and Addison’s Disease in a 12-Year-Old Boy

1
Paediatric Clinic, Azienda Ospedaliera di Terni, 05100 Terni, Italy
2
Pediatric Highly Intensive Care Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, 20122 Milan, Italy
3
Paediatric Clinic, Department of Surgical and Biomedical Sciences, Università degli Studi di Perugia, 06123 Perugia, Italy
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2017, 14(8), 855; https://doi.org/10.3390/ijerph14080855
Received: 4 July 2017 / Revised: 26 July 2017 / Accepted: 28 July 2017 / Published: 29 July 2017
(This article belongs to the Section Health Behavior, Chronic Disease and Health Promotion)
Background: Celiac disease (CD) is an autoimmune disorder deriving from an aberrant adaptive immune response against gluten-containing grains in genetically predisposed subjects. In a number of patients, CD is associated with one or more other autoimmune diseases. Primary Addison’s disease (AD) and CD may co-exist, although this association is relatively uncommon in children. In addition, it is not precisely defined whether a gluten-free diet influences the course of AD. Case presentation: A case of CD in a 12-year-old boy presenting as acute adrenal insufficiency is described here. A gluten-free diet had a significant therapeutic role in this case, wherein most of the clinical signs and symptoms of AD disappeared in a few days. In addition, the dosage of cortisol acetate, initially administered to treat the AD, was able to be rapidly reduced. Conclusion: This case highlights that CD can be associated with AD in children, and a gluten-free diet seems to positively influence the course of AD. View Full-Text
Keywords: Addison’s disease; autoimmune diseases; celiac disease; gluten-free diet Addison’s disease; autoimmune diseases; celiac disease; gluten-free diet
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MDPI and ACS Style

Miconi, F.; Savarese, E.; Miconi, G.; Cabiati, G.; Rapaccini, V.; Principi, N.; Esposito, S. Unusual Onset of Celiac Disease and Addison’s Disease in a 12-Year-Old Boy. Int. J. Environ. Res. Public Health 2017, 14, 855. https://doi.org/10.3390/ijerph14080855

AMA Style

Miconi F, Savarese E, Miconi G, Cabiati G, Rapaccini V, Principi N, Esposito S. Unusual Onset of Celiac Disease and Addison’s Disease in a 12-Year-Old Boy. International Journal of Environmental Research and Public Health. 2017; 14(8):855. https://doi.org/10.3390/ijerph14080855

Chicago/Turabian Style

Miconi, Francesco; Savarese, Emanuela; Miconi, Giovanni; Cabiati, Gabriele; Rapaccini, Valentina; Principi, Nicola; Esposito, Susanna. 2017. "Unusual Onset of Celiac Disease and Addison’s Disease in a 12-Year-Old Boy" Int. J. Environ. Res. Public Health 14, no. 8: 855. https://doi.org/10.3390/ijerph14080855

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