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Microalgae n-3 PUFAs Production and Use in Food and Feed Industries

GREENSEA, 3 Promenade du Sergent Jean-Louis Navarro, 34140 MÈZE, France
ALLMICROALGAE–Natural Products, Avenida 25 Abril, 2445-413 Pataias, Portugal
GREENTECH, Biopôle Clermont-Limagne, 63360 SAINT BEAUZIRE, France
ECREIN Team, UMR 1019 INRA-UcA, UNH (Human Nutrition Unity), University Clermont Auvergne, 63000 Clermont-Ferrand, France
Author to whom correspondence should be addressed.
Academic Editors: Andrew P. Desbois and Óscar Monroig
Mar. Drugs 2021, 19(2), 113;
Received: 15 January 2021 / Revised: 13 February 2021 / Accepted: 15 February 2021 / Published: 18 February 2021
(This article belongs to the Special Issue Marine Fatty Acids-2021)
N-3 polyunsaturated fatty acids (n-3 PUFAs), and especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are essential compounds for human health. They have been proven to act positively on a panel of diseases and have interesting anti-oxidative, anti-inflammatory or anti-cancer properties. For these reasons, they are receiving more and more attention in recent years, especially future food or feed development. EPA and DHA come mainly from marine sources like fish or seaweed. Unfortunately, due to global warming, these compounds are becoming scarce for humans because of overfishing and stock reduction. Although increasing in recent years, aquaculture appears insufficient to meet the increasing requirements of these healthy molecules for humans. One alternative resides in the cultivation of microalgae, the initial producers of EPA and DHA. They are also rich in biochemicals with interesting properties. After defining macro and microalgae, this review synthesizes the current knowledge on n-3 PUFAs regarding health benefits and the challenges surrounding their supply within the environmental context. Microalgae n-3 PUFA production is examined and its synthesis pathways are discussed. Finally, the use of EPA and DHA in food and feed is investigated. This work aims to define better the issues surrounding n-3 PUFA production and supply and the potential of microalgae as a sustainable source of compounds to enhance the food and feed of the future. View Full-Text
Keywords: microalgae; n-3 PUFA; EPA; DHA; food industry; feed industry microalgae; n-3 PUFA; EPA; DHA; food industry; feed industry
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MDPI and ACS Style

Remize, M.; Brunel, Y.; Silva, J.L.; Berthon, J.-Y.; Filaire, E. Microalgae n-3 PUFAs Production and Use in Food and Feed Industries. Mar. Drugs 2021, 19, 113.

AMA Style

Remize M, Brunel Y, Silva JL, Berthon J-Y, Filaire E. Microalgae n-3 PUFAs Production and Use in Food and Feed Industries. Marine Drugs. 2021; 19(2):113.

Chicago/Turabian Style

Remize, Marine, Yves Brunel, Joana L. Silva, Jean-Yves Berthon, and Edith Filaire. 2021. "Microalgae n-3 PUFAs Production and Use in Food and Feed Industries" Marine Drugs 19, no. 2: 113.

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