Next Article in Journal
Extract from the Zooxanthellate Jellyfish Cotylorhiza tuberculata Modulates Gap Junction Intercellular Communication in Human Cell Cultures
Previous Article in Journal
“Head-to-Side-Chain” Cyclodepsipeptides of Marine Origin
Open AccessArticle

Polyketides from a Marine-Derived Fungus Xylariaceae sp.

1
Key Laboratory of Marine Bio-Resources Sustainable Utilization, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, Guangdong, China
2
University of Chinese Academy of Sciences, Beijing 100049, China
3
New Drug Research & Development Center of North China Pharmaceutical Group Corporation, Shijiazhuang, Hebei 052260, China
*
Author to whom correspondence should be addressed.
Mar. Drugs 2013, 11(5), 1718-1727; https://doi.org/10.3390/md11051718
Received: 19 March 2013 / Revised: 22 April 2013 / Accepted: 25 April 2013 / Published: 21 May 2013
Eighteen polyketides (118) including six citrinin derivatives, two phenol derivatives, one cyclopentenone, two naphthol derivatives, and seven tetralone derivatives were isolated from the culture broth of a marine-derived fungal strain Xylariaceae sp. SCSGAF0086. Five of these compounds (1, 2, 8, 9, and 10) were new, and their structures were determined by spectroscopic methods. Compounds 4, 6, 7, and 17 showed enzyme-inhibitory activities towards several tested enzymes, and 6 and 7 showed strong antifouling activity against Bugula neritina larvae settlement. This is the first time that the antifouling and enzyme-inhibitory activities of these compounds has been reported. View Full-Text
Keywords: Xylariaceae sp.; polyketide; enzyme-inhibitory activity; antifouling activity Xylariaceae sp.; polyketide; enzyme-inhibitory activity; antifouling activity
Show Figures

Figure 1

MDPI and ACS Style

Nong, X.-H.; Zheng, Z.-H.; Zhang, X.-Y.; Lu, X.-H.; Qi, S.-H. Polyketides from a Marine-Derived Fungus Xylariaceae sp.. Mar. Drugs 2013, 11, 1718-1727.

Show more citation formats Show less citations formats

Article Access Map

1
Only visits after 24 November 2015 are recorded.
Back to TopTop