Next Article in Journal
Crambescidin-816 Acts as a Fungicidal with More Potency than Crambescidin-800 and -830, Inducing Cell Cycle Arrest, Increased Cell Size and Apoptosis in Saccharomyces cerevisiae
Previous Article in Journal
Antiproliferative Activity of Cyanophora paradoxa Pigments in Melanoma, Breast and Lung Cancer Cells
Article Menu

Export Article

Open AccessArticle

New Constituents from the Korean Sponge Plakortis simplex

Department of Oceanography, Kunsan National University, Jeonbuk 573-701, Korea
College of Pharmacy and Wonkwang-Oriental Medicines Research Institute, Institute of Biotechnology, Wonkwang University, Jeonbuk 570-749, Korea
Author to whom correspondence should be addressed.
Mar. Drugs 2013, 11(11), 4407-4418;
Received: 10 July 2013 / Revised: 30 September 2013 / Accepted: 14 October 2013 / Published: 5 November 2013
PDF [502 KB, uploaded 24 February 2015]


Six new cyclic peroxides (16) were isolated from the Korean sponge Plakortis simplex, along with two new alkylpyridinium alkaloids (7 and 8). The structures of these compounds were completely determined by a combination of NMR analysis and chemical reactions. Compounds 16 exhibited cytotoxic/antifungal activities against RAW264.7 cells and Candida albicans. View Full-Text
Keywords: Plakortis simplex; cyclic peroxide; cyclic peroxyketal; pyridinium; NMR Plakortis simplex; cyclic peroxide; cyclic peroxyketal; pyridinium; NMR

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Supplementary material


Share & Cite This Article

MDPI and ACS Style

Oh, J.S.; Hwang, B.S.; Kang, O.-H.; Kwon, D.-Y.; Rho, J.-R. New Constituents from the Korean Sponge Plakortis simplex. Mar. Drugs 2013, 11, 4407-4418.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top