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Volume 36
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10.21775/cimb.036.033
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Current Issues in Molecular Biology is published by MDPI from Volume 43 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Caister Press.
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Review

Microbiome: Effects of Ageing and Diet

by
Nuria Salazar
1,2,
Sonia González
2,3,
Alicja M. Nogacka
1,2,
David Rios-Covián
1,2,
Silvia Arboleya
1,2,
Miguel Gueimonde
1,2 and
Clara G. de los Reyes-Gavilán
1,2,*
1
Department of Microbiology and Biochemistry of Dairy Products, Instituto de Productos Lácteos de Asturias, Spanish Research Council (IPLA-CSIC), Villaviciosa, Spain
2
Diet, Microbiota and Health Research Team, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain
3
Department of Functional Biology, Faculty of Medicine, University of Oviedo, Oviedo, Spain
*
Author to whom correspondence should be addressed.
Curr. Issues Mol. Biol. 2020, 36(1), 33-62; https://doi.org/10.21775/cimb.036.033
Submission received: 6 June 2019 / Revised: 7 July 2019 / Accepted: 8 August 2019 / Published: 27 September 2019
Versions Notes

Abstract

The microbial community inhabiting our intestine, known as 'microbiota', and the ensemble of their genomes (microbiome) regulate important functions of the host, being essential for health maintenance. The recent development of next-generation sequencing (NGS) methods has greatly facilitated the study of the microbiota and has contributed to evidence of the strong influence exerted by age and diet. However, the precise way in which the diet and its components modify the functionality of the intestinal microbiome is far from being completely known. Changes in the intestinal microbiota occur during ageing, frequently accompanied by physiological changes of the digestive tract, modification of dietary patterns and impairment of the immune system. Establishing nutritional strategies aiming to counterbalance the specific alterations taking place in the microbiota during ageing would contribute to improved health status in the elderly. This review will analyse changes appearing in the intestinal microbiota from adulthood to old age and their association with dietary patterns and lifestyle factors.

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MDPI and ACS Style

Salazar, N.; González, S.; Nogacka, A.M.; Rios-Covián, D.; Arboleya, S.; Gueimonde, M.; de los Reyes-Gavilán, C.G. Microbiome: Effects of Ageing and Diet. Curr. Issues Mol. Biol. 2020, 36, 33-62. https://doi.org/10.21775/cimb.036.033

AMA Style

Salazar N, González S, Nogacka AM, Rios-Covián D, Arboleya S, Gueimonde M, de los Reyes-Gavilán CG. Microbiome: Effects of Ageing and Diet. Current Issues in Molecular Biology. 2020; 36(1):33-62. https://doi.org/10.21775/cimb.036.033

Chicago/Turabian Style

Salazar, Nuria, Sonia González, Alicja M. Nogacka, David Rios-Covián, Silvia Arboleya, Miguel Gueimonde, and Clara G. de los Reyes-Gavilán. 2020. "Microbiome: Effects of Ageing and Diet" Current Issues in Molecular Biology 36, no. 1: 33-62. https://doi.org/10.21775/cimb.036.033

APA Style

Salazar, N., González, S., Nogacka, A. M., Rios-Covián, D., Arboleya, S., Gueimonde, M., & de los Reyes-Gavilán, C. G. (2020). Microbiome: Effects of Ageing and Diet. Current Issues in Molecular Biology, 36(1), 33-62. https://doi.org/10.21775/cimb.036.033

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