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Volume 11
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10.21775/cimb.011.047
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Review

Saccharomyces boulardii Effects on Gastrointestinal Diseases

by
Galliano Zanello
,
François Meurens
,
Mustapha Berri
and
Henri Salmon
*
Institut National de la Recherche Agronomique (INRA), UR1282, Infectiologie Animale et Santé Publique, F-37380 Nouzilly (Tours), France
*
Author to whom correspondence should be addressed.
Curr. Issues Mol. Biol. 2009, 11(1), 47-58; https://doi.org/10.21775/cimb.011.047
Submission received: 7 February 2008 / Revised: 11 April 2008 / Accepted: 8 May 2008 / Published: 25 June 2008
Versions Notes

Abstract

Health benefits attributed to probiotics have been described for decades. They include the treatment and the prevention of gastrointestinal diseases, vaginal and urinary infections and allergies. Saccharomyces boulardii, a species of yeast widely distributed, has been described as a biotherapeutic agent since several clinical trials displayed its beneficial effects in the prevention and the treatment of intestinal infections and in the maintenance of inflammatory bowel disease. All these diseases are characterized by acute diarrhoea. Administration of the yeast in combination or not with an antibiotherapy has shown to decrease significantly the duration and the frequency of diarrhoea. Experimental studies elucidated partially the molecular mechanisms triggered to improve the host health. The discovery of its anti-inflammatory and immuno-modulatory activities in correlation with the advances in the understanding of mucosal immunology opens a new field of perspectives in S. boulardii therapeutic applications.
Keywords: health ; probiotics; gastrointestinal diseases; urinary infections ; allergies; Saccharomyces boulardii; yeast; biotherapeutic agent; intestinal infections ; inflammatory bowel disease; diarrhoea; S. boulardii health ; probiotics; gastrointestinal diseases; urinary infections ; allergies; Saccharomyces boulardii; yeast; biotherapeutic agent; intestinal infections ; inflammatory bowel disease; diarrhoea; S. boulardii

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MDPI and ACS Style

Zanello, G.; Meurens, F.; Berri, M.; Salmon, H. Saccharomyces boulardii Effects on Gastrointestinal Diseases. Curr. Issues Mol. Biol. 2009, 11, 47-58. https://doi.org/10.21775/cimb.011.047

AMA Style

Zanello G, Meurens F, Berri M, Salmon H. Saccharomyces boulardii Effects on Gastrointestinal Diseases. Current Issues in Molecular Biology. 2009; 11(1):47-58. https://doi.org/10.21775/cimb.011.047

Chicago/Turabian Style

Zanello, Galliano, François Meurens, Mustapha Berri, and Henri Salmon. 2009. "Saccharomyces boulardii Effects on Gastrointestinal Diseases" Current Issues in Molecular Biology 11, no. 1: 47-58. https://doi.org/10.21775/cimb.011.047

APA Style

Zanello, G., Meurens, F., Berri, M., & Salmon, H. (2009). Saccharomyces boulardii Effects on Gastrointestinal Diseases. Current Issues in Molecular Biology, 11(1), 47-58. https://doi.org/10.21775/cimb.011.047

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