Special Issue "Recent Advances in Organophosphorus Chemistry"
Deadline for manuscript submissions: closed (30 September 2016)
Prof. Dr. György Keglevich
Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1521 Budapest, Hungary
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Interests: organophosphorus chemistry (P-heterocycles, phospha -Michael reactions, Kabachnik-Fields (phospha-Mannich) reaction, C-P coupling reactions); green chemistry; MW chemistry; platinum complexes with P-ligands; synthesis of dronates; phase transfer catalysis
These days, organophosphorus (OP) chemistry forms an integrant part of synthetic organic chemistry. OP compounds are used as starting materials, intermediates, reagents, catalysts (phase transfer catalysts or P(III)-transition metal complexes), and solvents (ionic liquids (IL)) in research laboratories and in the industry. There are a lot of frequently applied reactions, such as reductions, the Wittig reaction and its variations, especially the catalytic versions, the Arbuzov reaction, the Pudovik reaction, the Mitsunobu reaction, the Kabachnik-Fields reaction, etc., which apply P-containing reagents. The simple deoxygenation of phosphine oxides is also a challenging field. Other reactions, e.g., homogeneous catalytic transformations or C–C coupling reactions involve P-ligands in the catalysts. There has been an enormous development in the field of chiral OP compounds. Methods have been elaborated for the resolution of tertiary phosphine oxides and for stereoselective OP transformations. The optically active P(III) species may be used as ligands in transition metal (Pt, Pd, etc.) complex catalysts making possible enantioselective transformations. The heterocyclic discipline may include P-heterocycles and classical O- and N-heterocycles with P-functions. A special field comprises P-containing or P-functionalized macrocycles and other macromolecules, like dendrimers. An up-to-date approach is to perform syntheses in the OP discipline in an environmentally-friendly manner. This may include the use of microwave or ultrasound. Solvent-free accomplishments are also interesting. At the other end, OP species (e.g., catalysts and ILs) may be tools in organic chemistry. Monitoring the reactions in order to optimize the conditions, or to observe reactive species is a challenging field. Theoretical calculations within OP chemistry is a developing field; these days stereostructures and mechanisms may be easily evaluated. A very important segment of OP chemistry, better to say a driving force for the development, is the pool of biologically active OP compounds (e.g., bisphosphonic derivatives and aminophosphonic species) that are searched and used as drugs, or plant protecting agents. The natural (e.g., peptide and amino acid) analogue P-compounds should also be mentioned. Lots of new phosphine oxides, phosphinates, phosphonates and phosphoric esters have been described that may obtain different kinds of application.
The OP Special Issue of Molecules will welcome all kind of submissions that fit the above outline.
Prof. Dr. György Keglevich
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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- organophosphorus chemistry
- Arbuzov reaction
- Pudovik reaction
- Kabachnik-Fields reaction
- Wittig reaction
- Mitsunobu reaction
- Hirao reaction
- phosphine chalcogenides
- phosphines, phosphinic acids
- phosphonic acids
- phosphine boranes
- phosphine complexes
- homogeneous catalysis
- ionic liquids
- theoretical calculations
- biologically active substrates
- P-containing drugs
- dronic acid derivatives