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Molecules 2013, 18(7), 8473-8484; doi:10.3390/molecules18078473
Article

Hydrophosphonylation of Nanoparticle Schiff Bases as a Mean for Preparation of Aminophosphonate-Functionalized Nanoparticles

1, 1 and 2,*
1 Department of Bioorganic Chemistry, Faculty of Chemistry, Wrocław University of Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wroclaw, Poland 2 Department of Chemical Engineering, University of Bath, Bath BA2 7AY, UK
* Author to whom correspondence should be addressed.
Received: 9 June 2013 / Revised: 9 July 2013 / Accepted: 15 July 2013 / Published: 18 July 2013
(This article belongs to the Special Issue Organophosphorus Chemistry)
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Abstract

The development of nanotechnology is responsible for an increase in the achievements in medical diagnostics and in the preparation of new therapeutic vehicles. In particular, magnetic nanoparticles with a modified surface are a very attractive alternative to deliver therapeutic agents. We describe the modification of the surface of the iron oxide nanoparticles with aminophosphonic acids by applying the classic hydrophosphonylation approach.
Keywords: magnetic nanoparticles; aminophosphonates; surface modification magnetic nanoparticles; aminophosphonates; surface modification
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Siemieniec, J.; Kafarski, P.; Plucinski, P. Hydrophosphonylation of Nanoparticle Schiff Bases as a Mean for Preparation of Aminophosphonate-Functionalized Nanoparticles. Molecules 2013, 18, 8473-8484.

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