Special Issue "Organophosphorus Chemistry"
Deadline for manuscript submissions: closed (31 July 2013)
Prof. Dr. György Keglevich
Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1521 Budapest, Hungary
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Interests: organophosphorus chemistry (P-heterocycles, phospha -Michael reactions, Kabachnik-Fields (phospha-Mannich) reaction, C-P coupling reactions); green chemistry; MW chemistry; platinum complexes with P-ligands; synthesis of dronates; phase transfer catalysis
These days, organophosphorus (OP) chemistry became an integrant part of synthetic organic chemistry. OP compounds are used as starting materials, reagents, catalysts (phase transfer catalysts or P(III)-transition metal complexes) and solvents (ionic liquids (IL)) in research laboratories and in the industry. A part of these applications are in the focus today. There are a lot of frequently used reactions, such as reductions, the Wittig reaction and its variations, the Arbuzov reaction, the Mitsunobu reaction etc. that apply P-containing reagents. Other reactions eg. homogeneous catalytic transformations or C-C coupling reactions involve P-ligands in the catalysts. There has been an enormous development in the field of chiral OP compounds. Methods have been elaborated for the resolution of tertiary phosphine oxides and for stereoselective OP transformations. The optically active P(III) species may be used in transition metal (Pt, Pd, etc.) complex catalysts promoting enantioselective transformations. The heterocyclic discipline may include P-heterocycles and classical O- and N-heterocycles with P-functions. A special field comprises P-containing macrocycles and other macromolecules, like dendrimers. An up-to-date approach is to perform syntheses in the OP discipline in an environmentally-friendly manner. This may include the use of microwave. At the other end, OP species (eg. catalysts and ILs) may be tools in general synthetic organic chemistry. Monitoring the reactions in order to optimize the conditions or to observe reactive species is a challenging field. Theoretical calculations within OP chemistry is also developing field; these days stereostructures and mechanisms may be easily evaluated. A very importanft segment od OP chemistry, better to say a driving force for the development, is the pool of biologically active OP compounds that are searched and used as drugs, or plant protecting agents. The natural analogue P-compounds (eg. peptide and aminoacid analogues) should also be mentioned. Lots of new phosphine oxides, phosphinates, phosphonates and phosphoric esters have been described that may obtain application on a broad scale.
The OP special issue of Molecules will welcome all kind of submissions that fit the above outline.
Prof. Dr. György Keglevich
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.
- organophosphorus chemistry
- phosphine chalcogenides
- phosphinic acids
- phosphonic acids
- phosphine boranes
- phosphine complexes
- homogeneous catalysis
- ionic liquids
- theoretical calculations
- biologically active substrates