Next Article in Journal
Advances in Organic and Organic-Inorganic Hybrid Polymeric Supports for Catalytic Applications
Next Article in Special Issue
Synthesis, Properties and Stereochemistry of 2-Halo-1,2λ5-oxaphosphetanes
Previous Article in Journal
Identification of the Main Intermediate Precursor of l-Ergothioneine Biosynthesis in Human Biological Specimens
Previous Article in Special Issue
Practical and Efficient Synthesis of α-Aminophosphonic Acids Containing 1,2,3,4-Tetrahydroquinoline or 1,2,3,4-Tetrahydroisoquinoline Heterocycles
Article Menu
Issue 10 (October) cover image

Export Article

Open AccessArticle
Molecules 2016, 21(10), 1295; doi:10.3390/molecules21101295

Palladium-Catalyzed Allylation/Benzylation of H-Phosphinate Esters with Alcohols

Department of Chemistry and Biochemistry, TCU Box 298860, Texas Christian University, Fort Worth, TX 76129, USA
*
Author to whom correspondence should be addressed.
Academic Editor: György Keglevich
Received: 10 September 2016 / Revised: 18 September 2016 / Accepted: 19 September 2016 / Published: 28 September 2016
(This article belongs to the Special Issue Recent Advances in Organophosphorus Chemistry)
View Full-Text   |   Download PDF [1527 KB, uploaded 28 September 2016]   |  

Abstract

The Pd-catalyzed direct alkylation of H-phosphinic acids and hypophosphorous acid with allylic/benzylic alcohols has been described previously. Here, the extension of this methodology to H-phosphinate esters is presented. The new reaction appears general, although its scope is narrower than with the acids, and its mechanism is likely different. Various alcohols are examined in their reaction with phosphinylidene compounds R1R2P(O)H. View Full-Text
Keywords: palladium; cross-coupling; alcohols; H-phosphinate esters; allylation; benzylation palladium; cross-coupling; alcohols; H-phosphinate esters; allylation; benzylation
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Fers-Lidou, A.; Berger, O.; Montchamp, J.-L. Palladium-Catalyzed Allylation/Benzylation of H-Phosphinate Esters with Alcohols. Molecules 2016, 21, 1295.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top