Special Issue "Frontiers in Nucleic Acid Chemistry"
Deadline for manuscript submissions: closed (15 July 2015)
Prof. Dr. Ramon Eritja
Institute for Advanced Chemistry of Catalonia, IQAC-CSIC, CIBER-BBN, Jordi Girona 18-26, 08034 Barcelona, Spain
Website | E-Mail
Interests: nucleic acid chemistry; DNA and RNA analogs: synthesis applications, molecular tools; RNA interference; DNA nanotechnology; G-quadruplex; Triplex, artificial DNA
Nucleic acids are the key molecules for transmitting genetic inheritance. The identification of DNA as the basis of genetic material and the elucidation of its structure stimulated the development of protocols for synthesizing defined oligonucleotides. Today, synthetic oligonucleotides that contain genetically encoded information have become emerging drugs and essential tools for biological, biomedical, and nanotechnology research. Novel oligonucleotide derivatives with tailored properties have been developed. Most of these new properties were obtained by modifying the structure or by introducing selected molecules, thus resulting in oligonucleotide conjugates or chimeras. In addition, artificial or modified nucleic acids, with novel hybridization properties, have been developed. The study of the properties of such nucleic acids brings together many different branches of science, such as molecular biology, chemistry, biochemistry, pharmaceuticals, medicine, materials science, and synthetic biology.
This Special Issue of Molecules will concentrate on the latest developments in nucleic acids chemistry. For this Special Issue, we encourage authors to submit research papers and comprehensive reviews describing nucleic acid derivatives with novel or improved structural and/or biomedical properties.
Prof. Dr. Ramon Eritja
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- modified oligonucleotides
- artificial nucleic acids
- xeno nucleic acids
- synthetic genes
- oligonucleotide conjugates
- RNA interference
- DNA nanobiotechnology
- fluorescent nucleic acids
- locked nucleic acids
- unlocked nucleic acids
- DNA repair
- Base-modified DNA
- DNA polymerase
- Circular nucleic acids
- NMR of nucleic acids
- Biophysical studies