Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (1)

Search Parameters:
Keywords = terminal end buds (TEB)

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
8 pages, 421 KiB  
Article
Differential Mammary Gland Development in FVB and C57Bl/6 Mice: Implications for Breast Cancer Research
by Mira B. MacLennan, Breanne M. Anderson and David W.L. Ma
Nutrients 2011, 3(11), 929-936; https://doi.org/10.3390/nu3110929 - 25 Oct 2011
Cited by 18 | Viewed by 9157
Abstract
A growing body of research suggests a linkage between pubertal mammary gland development and environmental factors such as diet as modifiers of long term breast cancer risk. Much of this research is dependent upon mouse models, which may vary between studies. However, effects [...] Read more.
A growing body of research suggests a linkage between pubertal mammary gland development and environmental factors such as diet as modifiers of long term breast cancer risk. Much of this research is dependent upon mouse models, which may vary between studies. However, effects may be strain dependent and further modified by diet, which has not been previously examined. Therefore, the objective of the present study was to determine whether mammary gland development differs between FVB and C57Bl/6 strains on diets containing either n-6 or n-3 polyunsaturated fats. Developmental measures related to onset of puberty and mammary gland development differed between strains. Mice fed the n-3 polyunsaturated fatty acids (PUFA) diet were shown to have lower numbers of terminal end buds, a marker of mammary gland development. This study helps to further clarify differences in development and dietary response between FVB and C57Bl/6 mice in order to more appropriately relate mammary gland research to human populations. Full article
(This article belongs to the Special Issue Diet and Cancer Prevention)
Show Figures

Figure 1

Back to TopTop