Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (1)

Search Parameters:
Keywords = supracolloidal chemistry

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
12 pages, 1265 KiB  
Communication
Supracolloidal Assemblies as Sacrificial Templates for Porous Silk-Based Biomaterials
by John G. Hardy, Chiara E. Ghezzi, Richard J. Saballos, David L. Kaplan and Christine E. Schmidt
Int. J. Mol. Sci. 2015, 16(9), 20511-20522; https://doi.org/10.3390/ijms160920511 - 28 Aug 2015
Cited by 6 | Viewed by 6846
Abstract
Tissues in the body are hierarchically structured composite materials with tissue-specific properties. Urea self-assembles via hydrogen bonding interactions into crystalline supracolloidal assemblies that can be used to impart macroscopic pores to polymer-based tissue scaffolds. In this communication, we explain the solvent interactions governing [...] Read more.
Tissues in the body are hierarchically structured composite materials with tissue-specific properties. Urea self-assembles via hydrogen bonding interactions into crystalline supracolloidal assemblies that can be used to impart macroscopic pores to polymer-based tissue scaffolds. In this communication, we explain the solvent interactions governing the solubility of urea and thereby the scope of compatible polymers. We also highlight the role of solvent interactions on the morphology of the resulting supracolloidal crystals. We elucidate the role of polymer-urea interactions on the morphology of the pores in the resulting biomaterials. Finally, we demonstrate that it is possible to use our urea templating methodology to prepare Bombyx mori silk protein-based biomaterials with pores that human dermal fibroblasts respond to by aligning with the long axis of the pores. This methodology has potential for application in a variety of different tissue engineering niches in which cell alignment is observed, including skin, bone, muscle and nerve. Full article
(This article belongs to the Special Issue Supramolecular Interactions)
Show Figures

Graphical abstract

Back to TopTop