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  • Open Access
2 Citations
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GBT1118, a Voxelotor Analog, Ameliorates Hepatopathy in Sickle Cell Disease

  • Elio Haroun,
  • Seah H. Lim and
  • Dibyendu Dutta
Medicina2024, 60(10), 1581;https://doi.org/10.3390/medicina60101581

26 September 2024

Background and Objectives: In sickle cell disease (SCD), hepatopathy is a cumulative consequence of ischemia/reperfusion (I/R) injury from a vaso-occlusive crisis, tissue inflammation, and iron overload due to blood transfusion. Hepatopathy is a majo...

(This article belongs to the Section Gastroenterology & Hepatology)
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  • Article
  • Open Access
51 Citations
8,987 Views
15 Pages
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Hepatobiliary Complications in Children with Sickle Cell Disease: A Retrospective Review of Medical Records from 616 Patients

  • Slimane Allali,
  • Mariane de Montalembert,
  • Valentine Brousse,
  • Claire Heilbronner and ,
  • Melissa Taylor,
  • Josephine Brice,
  • Elisabetta Manzali,
  • Nicolas Garcelon and
  • Florence Lacaille
  • + 4 authors+ 0 author
J. Clin. Med.2019, 8(9), 1481;https://doi.org/10.3390/jcm8091481

18 September 2019

Hepatobiliary complications in children with sickle cell disease (SCD) are rarely reported but can be life-threatening. We retrospectively assessed their prevalence in a cohort of 616 children followed in a French university-hospital SCD reference ce...

(This article belongs to the Special Issue Sickle Cell Anemia: From Genetic Epidemiology to New Therapeutic Strategies)
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