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Diabetic foot ulcers (DFUs) are a serious complication of diabetes, associated with high recurrence and amputation rates. Adherence to offloading devices is critical for wound healing but remains inadequately monitored in real-world settings. This study evaluates the SmartBoot edge-computing system—a wearable, real-time remote monitoring solution integrating an inertial measurement unit (Sensoria Core) and smartwatch—for its validity in quantifying cadence and step count as digital biomarkers of frailty, and for detecting adherence. Twelve healthy adults wore two types of removable offloading boots (Össur and Foot Defender) during walking tasks at varied speeds; system outputs were validated against a gold-standard wearable and compared with staff-recorded adherence logs. Additionally, user experience was assessed using the Technology Acceptance Model (TAM) in healthy participants (n = 12) and patients with DFU (n = 81). The SmartBoot demonstrated high accuracy in cadence and step count across conditions (bias < 5.5%), with an adherence detection accuracy of 96% (Össur) and 97% (Foot Defender). TAM results indicated strong user acceptance and perceived ease of use across both cohorts. These findings support the SmartBoot system’s potential as a valid, scalable solution for real-time remote monitoring of adherence and mobility in DFU management. Further clinical validation in ongoing studies involving DFU patients is underway. Full article

The objective of this manuscript is to reveal that the challenge in understanding the ethical consequences of a post-human condition characterizing trans-humanist ontology is linked to postmodern epistemology lacking any metaphysical and theological essence. The introductory section provides an overview of trans-humanist thought and the concerns deliberated against it at the recent conference titled A.I Ethics: An Abrahamic Commitment to the Rome Call, charting a path ensuring that technological innovations do not undermine the ethical, spiritual, and moral values animating the telos of the human being. The second section traces the philosophical genealogy of trans-humanism from the Age of Reason (i.e., modern epistemology) to our current Age of Feeling (i.e., postmodern epistemology). This section also stresses that the ontology accenting both periods—the death of God and the death of human—is latent in trans-humanist ideology, which seeks to extinguish the quest of knowing God with an ateleological state that crucifies the human in pursuit of worshipping technology. The third section scrutinizes the conceptual framework of trans-humanism by deconstructing concepts structuring its worldview such as Singularity, Artificial Super Intelligence, and the pseudo-religion known as Dataism. Additionally, this section examines how trans-humanist proponents—while adhering to postmodern philosophy—alter the definitions of sacred concepts that exclusively animate a human state of being, such as consciousness, intelligence, and awareness, by anthropomorphizing AI. The final section recalls the wisdom of the Nicomachean Ethics and the Alchemy of Happiness, composed—respectively—by Aristotle and Al-Ghazali. It highlights the immoral significances of choosing to ignore the implications of Dataism and its techno-scientific objectives, which obscure the use of techne in a virtuous manner attaining eudaimonia and the essence of humanness seeking a path—using God-given sensoria—knowledge of Divine Beauty. Full article