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Keywords = ortho-silylaryl triflate

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10 pages, 1213 KiB  
Communication
An Alternative Method for Generating Arynes from ortho-Silylaryl Triflates: Activation by Cesium Carbonate in the Presence of a Crown Ether
by Suguru Yoshida, Yuki Hazama, Yuto Sumida, Takahisa Yano and Takamitsu Hosoya
Molecules 2015, 20(6), 10131-10140; https://doi.org/10.3390/molecules200610131 - 1 Jun 2015
Cited by 62 | Viewed by 11993
Abstract
An alternative method for generating arynes from ortho-silylaryl triflates using cesium carbonate and 18-crown-6 is reported. The method was efficiently applied to a variety of reactions between several arynes and arynophiles. We also demonstrated that the efficiency of aryne generation is significantly [...] Read more.
An alternative method for generating arynes from ortho-silylaryl triflates using cesium carbonate and 18-crown-6 is reported. The method was efficiently applied to a variety of reactions between several arynes and arynophiles. We also demonstrated that the efficiency of aryne generation is significantly affected by the alkali metal countercation of the carbonate. Full article
(This article belongs to the Special Issue Development and Application of Aryne Chemistry in Organic Synthesis)
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