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Keywords = lymphocyte inhibitory factor A/EHEC factor for adherence-1

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9 pages, 145 KB  
Review
The Role of Lymphostatin/EHEC Factor for Adherence-1 in the Pathogenesis of Gram Negative Infection
by Jan-Michael A. Klapproth
Toxins 2010, 2(5), 954-962; https://doi.org/10.3390/toxins2050954 - 5 May 2010
Cited by 8 | Viewed by 9225
Abstract
Lymphostatin/EHEC factor for adherence-1 is a novel large toxin represented in various Gram negative bacteria, highly associated with the development of infectious diarrhea and hemolytic uremic syndrome. In vitro and in vivo experiments identified lymphostatin/EFA-1 as a toxin with a central role in [...] Read more.
Lymphostatin/EHEC factor for adherence-1 is a novel large toxin represented in various Gram negative bacteria, highly associated with the development of infectious diarrhea and hemolytic uremic syndrome. In vitro and in vivo experiments identified lymphostatin/EFA-1 as a toxin with a central role in the pathogenesis of Gram negative bacteria, responsible for bacterial adhesion, intestinal colonization, immunosuppression, and disruption of gut epithelial barrier function. Full article
(This article belongs to the Special Issue Enterotoxins)
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