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Keywords = isomünchnones

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13 pages, 122 KiB  
Article
Design and Synthesis of a Conformationally Rigid Mimic of the Dihydropyrimidine Calcium Channel Modulator SQ 32,926
by Birgit Jauk, Tetiana Pernat and C. Oliver Kappe
Molecules 2000, 5(3), 227-239; https://doi.org/10.3390/50300227 - 3 Mar 2000
Cited by 129 | Viewed by 7787
Abstract
A conformationally rigid polyheterocycle (3) which mimics the putative receptorbound conformation of dihydropyridine-type calcium channel modulators is prepared in a seven-step reaction sequence based on a Biginelli-type cyclocondensation reaction. Full article
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