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Keywords = hepatoenteric collaterals

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11 pages, 1589 KiB  
Article
Temporary Reversal of Hepatoenteric Collaterals during 90Y Radioembolization Planning and Administration
by Peiman Habibollahi, Bruno C. Odisio, Varshana Gurusamy, Joshua D. Kuban, Rony Avritscher, Mohamed E. Abdelsalam, Beth A. Chasen, Ravi Murthy and Armeen Mahvash
Curr. Oncol. 2022, 29(12), 9582-9592; https://doi.org/10.3390/curroncol29120753 - 6 Dec 2022
Cited by 1 | Viewed by 2241
Abstract
Purpose: This paper aims to evaluate the safety and efficacy of the temporary redirection of blood flow of hepatoenteric collaterals using a balloon catheter in the common hepatic artery (CHA) to prevent the nontarget deposition of 90Y microspheres. Materials and Methods: In [...] Read more.
Purpose: This paper aims to evaluate the safety and efficacy of the temporary redirection of blood flow of hepatoenteric collaterals using a balloon catheter in the common hepatic artery (CHA) to prevent the nontarget deposition of 90Y microspheres. Materials and Methods: In this retrospective single-center study of patients who received 90Y radioembolization (RE) from September 2010 to September 2015, diagnostic (67 patients) or treatment (72 patients) angiograms with the attempted use of a balloon catheter in the CHA to temporarily direct blood flow away from the hepatoenteric arteries were analyzed. SPECT/CT nuclear scintigraphy was performed after both diagnosis and treatment. Results: Overall, only 12 hepatoenteric arteries in 11 patients required embolization due to persistent hepatoenteric flow despite the use of the balloon occlusion technique in a total of 86 patients. Physicians performed the 90Y RE using balloon occlusion with glass (n = 22) or resin (n = 50) microspheres. Over 80% administration of the prescribed 90Y dose was accomplished in 34 (67%) resin and 20 (95%) glass microsphere patients. Post-treatment 90Y RE scintigraphy confirmed the absence of extrahepatic activity in all patients. One grade 2 gastrointestinal ulcer was present after 90 days of follow-up. Conclusion: Temporary CHA occlusion with a balloon catheter is a reliable and reproducible alternative to the conventional coil embolization of hepatoenteric arteries during diagnostic Tc-99m macroaggregated albumin and therapeutic 90Y RE delivery. Full article
(This article belongs to the Special Issue Hepatobiliary Malignancies: Recent Advancements and Future Directions)
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