Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (1)

Search Parameters:
Keywords = etamsylate cephalosporins

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
18 pages, 5868 KB  
Article
Spectrophotometric Determination of Cefepime Hydrochloride, Cefoperazone Sodium, Ceftazidime Pentahydrate. Cefuroxime Sodium and Etamsylate Using Ammonium Molybdate
by Marwa S. Elazazy, Abdalla Shalaby, M. N. Elbolkiny and Hawa M. Khalil
Sci. Pharm. 2003, 71(3), 211-228; https://doi.org/10.3797/scipharm.aut-03-20 - 20 Jul 2003
Cited by 26 | Viewed by 1990
Abstract
A simple, rapid and sensitive spectrophotometric method has been developed for the quantitative determination of five drugs of pharmaceutical interest; cefepime HCI , cefoperazone Na , ceftazidime pentahydrate , cefuroxime Na and etamsylate in pure form as well as in pharmaceuticals. The method [...] Read more.
A simple, rapid and sensitive spectrophotometric method has been developed for the quantitative determination of five drugs of pharmaceutical interest; cefepime HCI , cefoperazone Na , ceftazidime pentahydrate , cefuroxime Na and etamsylate in pure form as well as in pharmaceuticals. The method is based on the reduction of the chromogenic agent , ammonium molybdate (Mo6+), to molybdenum blue (Mo5+) by the examined drugs in sulphuric acid medium and by aid of heating in boiling water bath. The resulting "blue coloured" product possess a characteristic λmax at 695-716 nm. Beers law is obeyed over the concentration range of 2-70 μg ml-1 with molar absorpitivities ranging from 2.704×10-3–24.14×10-3 L.mol-1.cm-1 and Sandell sensitivities ranging from 1.03x10-3–5.4x10-3 μg cm-2. The proposed method has been applied successfully for the determination of the examined drugs both in pure form and in pharmaceutical formulations. The accuracy and precision of the proposed method are comparable with those of the reported methods . Full article
Back to TopTop