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Keywords = embryokine

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14 pages, 755 KiB  
Review
Cytokines That Serve as Embryokines in Cattle
by Alan D. Ealy, Savannah L. Speckhart and Lydia K. Wooldridge
Animals 2021, 11(8), 2313; https://doi.org/10.3390/ani11082313 - 5 Aug 2021
Cited by 15 | Viewed by 4517
Abstract
The term “embryokine” has been used to denote molecules produced by the endometrium, oviduct, or by embryo itself that will influence embryo development. Several cytokines have been identified as embryokines in cattle and other mammals. This review will describe how these cytokines function [...] Read more.
The term “embryokine” has been used to denote molecules produced by the endometrium, oviduct, or by embryo itself that will influence embryo development. Several cytokines have been identified as embryokines in cattle and other mammals. This review will describe how these cytokines function as embryokines, with special emphasis being placed on their actions on in vitro produced (IVP) bovine embryos. Embryokines are being explored for their ability to overcome the poor development rates of IVP embryos and to limit post-transfer pregnancy retention efficiencies that exist in IVP embryos. This review will focus on describing two of the best-characterized cytokines, colony-stimulating factor 2 and interleukin 6, for their ability to modify bovine embryo quality and confirmation, promote normal fetal development, and generate healthy calves. Additional cytokines will also be discussed for their potential to serve as embryokines. Full article
(This article belongs to the Special Issue Maternal Influence on Animal Health and Performance)
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