The epidemiological features of
Cryptosporidium infection among school-age children in China still remain unclear. Hereby, a cross-sectional study of 1637 children aged 3–9 years was designed to investigate the risk factors and spatial clusters of
Cryptosporidium infection in a rural region of Eastern
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The epidemiological features of
Cryptosporidium infection among school-age children in China still remain unclear. Hereby, a cross-sectional study of 1637 children aged 3–9 years was designed to investigate the risk factors and spatial clusters of
Cryptosporidium infection in a rural region of Eastern China. Stool specimens collected from participants were examined using the auramine-phenol and modified acid-fast staining. Univariable and multivariable analyses were performed to identify the risk factors of
Cryptospordium infection. The spatial clusters were analyzed by a discrete Poisson model using SaTScan software. Our results showed that the overall prevalence of
Cryptosporidium infection was 11‰ in the research region. At the age of 3–6 years (odds ratios (OR) = 3.072, 95% confidence intervals (CI)
: 1.001–9.427), not washing hands before eating and after defecation (OR = 3.003, 95% CI: 1.060–8.511) were recognized as risk factors. Furthermore, a high-risk spatial cluster (relative risk = 4.220,
p = 0.025) was identified. These findings call for effective sustainable interventions including family and school-based hygienic education to reduce the prevalence of
Cryptosporidium infection. Therefore, an early warning system based spatiotemporal models with risk factors is required to further improve the effectiveness and efficiency of cryptosporidiosis control in the future.
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