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Keywords = bis-spiroacetals

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11 pages, 205 KB  
Article
Radical Oxidative Cyclization of Spiroacetals to Bis-spiroacetals: An Overview
by Margaret A. Brimble
Molecules 2004, 9(6), 394-404; https://doi.org/10.3390/90600394 - 31 May 2004
Cited by 20 | Viewed by 10276
Abstract
The use of iodobenzene diacetate and iodine under photolytic conditions provides and efficient method for the oxidative cyclization of spiroacetals bearing an hydroxyalkyl side chain to bis-spiroacetals. An overview is provided of the use of this reaction for the synthesis of several bis-spiroacetal [...] Read more.
The use of iodobenzene diacetate and iodine under photolytic conditions provides and efficient method for the oxidative cyclization of spiroacetals bearing an hydroxyalkyl side chain to bis-spiroacetals. An overview is provided of the use of this reaction for the synthesis of several bis-spiroacetal containing natural products such as the polyether antibiotics salinomycin and CP44,161 and the shellfish toxins, the spirolides. Full article
(This article belongs to the Special Issue RACI 2003 symposium)
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