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Keywords = atypical (pathological) reaction of an organism

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18 pages, 277 KiB  
Article
The Relationship between Symmetry and Specific Properties of Supramolecular Systems
by Yuriy Gorovoy
Symmetry 2022, 14(10), 2070; https://doi.org/10.3390/sym14102070 - 4 Oct 2022
Cited by 6 | Viewed by 1429
Abstract
Released agent is a supramolecular system formed around nanobubbles in highly diluted solutions of substances subjected to technological processing. Released agent retains the structure and symmetry of the supramolecular system of the dissolved substance. It has two specific properties: (1) when combined with [...] Read more.
Released agent is a supramolecular system formed around nanobubbles in highly diluted solutions of substances subjected to technological processing. Released agent retains the structure and symmetry of the supramolecular system of the dissolved substance. It has two specific properties: (1) when combined with the original substance, it modifies its effect on an organism; (2) and it could cause an atypical pathological reaction in some individuals. These properties could be due to the transmission of symmetry from released agent to the receptor in the molecular recognition reaction by deforming the receptor structure. A theoretical analysis of these properties was carried out using methods of statistical thermodynamics of complex systems, chemical thermodynamics of supramolecular systems, and analytical mechanics. The released agent’s modifying effect is a phenomenon of the receptor pre-organization in the molecular recognition reaction. The selective ability and free energy of complex formation of released agent (from highly diluted antibodies to the beta-subunit of the insulin receptor) with the insulin receptor was evaluated. The atypical pathological reaction of some individuals to released agents resembles a resonance phenomenon that occurs when the symmetries (structures) of released agent and the receptor coincide. The obtained results show a possibility to investigate released agents’ properties not only empirically, but also using the methods of theoretical physics. Full article
14 pages, 251 KiB  
Review
The Spatial Homeostasis Hypothesis
by Oleg Epstein
Symmetry 2018, 10(4), 103; https://doi.org/10.3390/sym10040103 - 10 Apr 2018
Cited by 63 | Viewed by 6563
Abstract
From studies on the effects of “high dilutions” on organisms, it was found that their administration induces a delicate physiological (molecular and cellular) response. Occasionally, physiological reactions can become atypical (pathological) individual reactions. To resolve this paradox, the spatial homeostasis hypothesis has been [...] Read more.
From studies on the effects of “high dilutions” on organisms, it was found that their administration induces a delicate physiological (molecular and cellular) response. Occasionally, physiological reactions can become atypical (pathological) individual reactions. To resolve this paradox, the spatial homeostasis hypothesis has been proposed. It considers pathological processes as tools used by living systems, in order to retain their spatial integrity (symmetry), allowing them to properly reflect the geometry of the surrounding world and thus, to be a part of the evolutionary process. This article addresses an interdisciplinary subject and is aimed at natural scientists (physicists, chemists, and biologists) as well as philosophers. Full article
(This article belongs to the Special Issue Symmetry: Anniversary Feature Papers 2018)
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