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Keywords = Takachi virus

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13 pages, 4015 KiB  
Article
Conserved Sequences in the 5′ and 3′ Untranslated Regions of Jingmenvirus Group Representatives
by Alexander G. Litov, Egor V. Okhezin, Ivan S. Kholodilov, Oxana A. Belova and Galina G. Karganova
Viruses 2023, 15(4), 971; https://doi.org/10.3390/v15040971 - 15 Apr 2023
Cited by 2 | Viewed by 2639
Abstract
The Jingmenvirus group (JVG), with members such as Jingmen tick virus (JMTV), Alongshan virus (ALSV), Yanggou tick virus (YGTV), and Takachi virus (TAKV), is drawing attention due to evidence of it causing disease in humans and its unique genome architecture. In the current [...] Read more.
The Jingmenvirus group (JVG), with members such as Jingmen tick virus (JMTV), Alongshan virus (ALSV), Yanggou tick virus (YGTV), and Takachi virus (TAKV), is drawing attention due to evidence of it causing disease in humans and its unique genome architecture. In the current work, complete untranslated regions (UTRs) of four strains of ALSV and eight strains of YGTV were obtained. An analysis of these sequences, as well as JVG sequences from GenBank, uncovered several regions within viral UTRs that were highly conserved for all the segments and viruses. Bioinformatics predictions suggested that the UTRs of all the segments of YGTV, ALSV, and JMTV could form similar RNA structures. The most notable feature of these structures was a stable stem-loop with one (5′ UTR) or two (3′ UTR) AAGU tetraloops on the end of a hairpin. Full article
(This article belongs to the Special Issue Molecular Epidemiology, Evolution, and Dispersion of Flaviviruses)
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14 pages, 2083 KiB  
Article
Detection of Jingmenviruses in Japan with Evidence of Vertical Transmission in Ticks
by Daisuke Kobayashi, Ryusei Kuwata, Toshiya Kimura, Hiroshi Shimoda, Ryosuke Fujita, Astri Nur Faizah, Izumi Kai, Ryo Matsumura, Yudai Kuroda, Shumpei Watanabe, Sawako Kuniyoshi, Takeo Yamauchi, Mamoru Watanabe, Yukiko Higa, Toshihiko Hayashi, Hiroto Shinomiya, Ken Maeda, Shinji Kasai, Kyoko Sawabe and Haruhiko Isawa
Viruses 2021, 13(12), 2547; https://doi.org/10.3390/v13122547 - 19 Dec 2021
Cited by 32 | Viewed by 5471
Abstract
Jingmen tick virus (JMTV) and the related jingmenvirus-termed Alongshan virus are recognized as globally emerging human pathogenic tick-borne viruses. These viruses have been detected in various mammals and invertebrates, although their natural transmission cycles remain unknown. JMTV and a novel jingmenvirus, tentatively named [...] Read more.
Jingmen tick virus (JMTV) and the related jingmenvirus-termed Alongshan virus are recognized as globally emerging human pathogenic tick-borne viruses. These viruses have been detected in various mammals and invertebrates, although their natural transmission cycles remain unknown. JMTV and a novel jingmenvirus, tentatively named Takachi virus (TAKV), have now been identified during a surveillance of tick-borne viruses in Japan. JMTV was shown to be distributed across extensive areas of Japan and has been detected repeatedly at the same collection sites over several years, suggesting viral circulation in natural transmission cycles in these areas. Interestingly, these jingmenviruses may exist in a host tick species-specific manner. Vertical transmission of the virus in host ticks in nature was also indicated by the presence of JMTV in unfed host-questing Amblyomma testudinarium larvae. Further epidemiological surveillance and etiological studies are necessary to assess the status and risk of jingmenvirus infection in Japan. Full article
(This article belongs to the Section Invertebrate Viruses)
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