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  • Article
  • Open Access
5 Citations
3,378 Views
19 Pages

Fluorescent Rhein-Loaded Liposomes for In Vivo Biodistribution Study

  • Silviu Iulian Filipiuc,
  • Natalia Simionescu,
  • Gabriela Dumitrița Stanciu,
  • Adina Coroaba,
  • Narcisa Laura Marangoci,
  • Leontina Elena Filipiuc,
  • Mariana Pinteala,
  • Cristina Mariana Uritu and
  • Bogdan Ionel Tamba

Objectives: This work aimed to develop and investigate liposomes incorporating Rhein (Lip-Rh) into the liposomal membrane to enhance the compound’s water solubility and oral bioavailability. Methods: Liposomes were produced by the thin lipid fi...

(This article belongs to the Special Issue Nanotechnology Applied in Prevention, Diagnosis and Treatment of Cancer)
  • Review
  • Open Access
772 Views
30 Pages

Anthraquinone-Loaded Liposomes for TAM Reprogramming in Triple-Negative Breast Cancer: Mechanistic Rationale, Delivery Logic, and Translational Challenges

  • Limin Zhai,
  • Juan Liu,
  • Lizhen Mu,
  • Cuiping Li,
  • Siyuan Zhao,
  • Ting Li,
  • Qiuzhen Zhu,
  • Xiaoli Hou,
  • Kourong Shi and
  • Wei Fan

Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by limited actionable targets, early recurrence, metastatic propensity, and variable responses to immune checkpoint blockade. Therapeutic resistance is closely associated wit...

(This article belongs to the Section Drug Delivery and Controlled Release)