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Keywords = N-benzylaminobenzylphosphonates

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12 pages, 2247 KB  
Article
Three-Component Reaction of Benzylamines, Diethyl Phosphite and Triethyl Orthoformate: Dependence of the Reaction Course on the Structural Features of the Substrates and Reaction Conditions
by Patrycja Miszczyk, Ilona Turowska-Tyrk, Paweł Kafarski and Ewa Chmielewska
Molecules 2017, 22(3), 450; https://doi.org/10.3390/molecules22030450 - 11 Mar 2017
Cited by 4 | Viewed by 7840
Abstract
The reaction between benzyl amines, triethyl orthoformate, and diethyl phosphite affords either bisphosphonic (compound 1) or N-benzylaminobenzylphosphonic (compound 2) acid depending on the reaction conditions. The final output of the reaction can be manipulated by the choice of reaction conditions, [...] Read more.
The reaction between benzyl amines, triethyl orthoformate, and diethyl phosphite affords either bisphosphonic (compound 1) or N-benzylaminobenzylphosphonic (compound 2) acid depending on the reaction conditions. The final output of the reaction can be manipulated by the choice of reaction conditions, particularly the molar ratio of substrates. Full article
(This article belongs to the Special Issue Women in Organic Chemistry)
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