Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (1)

Search Parameters:
Keywords = 8-geranyloxypsolaren

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
8 pages, 281 KB  
Article
Cytotoxic Constituents from the Stems of Clausena lansium (Lour.) Skeels
by Hai Yan Jiang, Cheng Fang Wang, Li Fan, Kai Yang, Jiang Bin Feng, Zhu Feng Geng, Jing Xu, Zhi Wei Deng, Shu Shan Du and Hai Bo Yin
Molecules 2013, 18(9), 10768-10775; https://doi.org/10.3390/molecules180910768 - 3 Sep 2013
Cited by 18 | Viewed by 7242
Abstract
Six compounds were isolated from the stems of Clausena lansium (Lour.) Skeels by repeated sillica gel column chromatography. Their chemical structures were elucidated on the basic of physicochemical and spectroscopic data. Among them, 8-geranyloxypsolaren (3) and 2-methoxy-1-(3-methyl-buten-1-yl)-9H-carbazole-3-carbaldehyde (6 [...] Read more.
Six compounds were isolated from the stems of Clausena lansium (Lour.) Skeels by repeated sillica gel column chromatography. Their chemical structures were elucidated on the basic of physicochemical and spectroscopic data. Among them, 8-geranyloxypsolaren (3) and 2-methoxy-1-(3-methyl-buten-1-yl)-9H-carbazole-3-carbaldehyde (6) were isolated for the first time from this plant. These compounds were screened for cytotoxicity in human cervical cancer (Hela), leukemia (K562), lung cancer (A549), non-small lung carcinoma (H1299) and liver cancer (SMMC-7721). Within the series of cytotoxic tests, compounds 46 displayed potent cytotoxic activity against H1299 and SMMC-7721, with the IC50 values of 6.19 to 26.84 μg/mL. Full article
Show Figures

Figure 1

Back to TopTop