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Authors = Yoshihiro Okutani

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13 pages, 497 KiB  
Article
A Longitudinal Study of the Relationship Between Lower Extremity Field Tests and Medial Elbow Injuries in Elementary School Baseball Players
by Maki Tanaka, Takuma Okutani, Shohei Maruyama, Kenji Suehiro, Tomoyuki Matsui, Machiko Hiramoto, Yoshikazu Azuma, Tetsuya Miyazaki, Megumi Gonno, Teruo Nomura, Kyosuke Oku, Yuya Watanabe, Yoshihiro Kai, Minoru Takeshima, Toru Morihara and Noriyuki Kida
Int. J. Environ. Res. Public Health 2024, 21(11), 1518; https://doi.org/10.3390/ijerph21111518 - 14 Nov 2024
Viewed by 1379
Abstract
This study aimed to examine prospectively the relationship between the deep squatting test and medial elbow injuries in elementary school baseball players and to determine the usefulness of the lower extremity field test in throwing injuries. The participants were 254 players who had [...] Read more.
This study aimed to examine prospectively the relationship between the deep squatting test and medial elbow injuries in elementary school baseball players and to determine the usefulness of the lower extremity field test in throwing injuries. The participants were 254 players who had participated in preseason medical checkups in both 2019 and 2020 and had no problems with the 2019 medical checkups. The evaluation parameters included ultrasonography examination, physical examination, and three types of deep squatting tests. The success rate of deep squatting tests was significantly lower in the injured group than in the non-injured group in the medial elbow injuries. By the difficulty level, the backward test in the deep squatting test was more likely to predict medial elbow injuries than the forward and middle tests. Furthermore, there was a significant difference in the squatting test and medial elbow injuries by grades. In conclusion, this is the first prospective study to provide evidence that the deep squatting tests, classified by difficulty level, can predict the risk of subsequent medial elbow injuries in elementary school players. The deep squatting test may be useful as a field test for lower extremity flexibility that can be performed by athletes and instructors, as it can predict the risk of subsequent medial elbow injuries. Full article
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10 pages, 1065 KiB  
Communication
Single Amino Acid Substitution in the Matrix Protein of Rabies Virus Is Associated with Neurovirulence in Mice
by Michiko Harada, Aya Matsuu, Yoshihiro Kaku, Akiko Okutani, Yusuke Inoue, Guillermo Posadas-Herrera, Satoshi Inoue and Ken Maeda
Viruses 2024, 16(5), 699; https://doi.org/10.3390/v16050699 - 28 Apr 2024
Cited by 2 | Viewed by 2222
Abstract
Rabies is a fatal encephalitic infectious disease caused by the rabies virus (RABV). RABV is highly neurotropic and replicates in neuronal cell lines in vitro. The RABV fixed strain, HEP-Flury, was produced via passaging in primary chicken embryonic fibroblast cells. HEP-Flury showed [...] Read more.
Rabies is a fatal encephalitic infectious disease caused by the rabies virus (RABV). RABV is highly neurotropic and replicates in neuronal cell lines in vitro. The RABV fixed strain, HEP-Flury, was produced via passaging in primary chicken embryonic fibroblast cells. HEP-Flury showed rapid adaptation when propagated in mouse neuroblastoma (MNA) cells. In this study, we compared the growth of our previously constructed recombinant HEP (rHEP) strain—based on the sequence of the HEP (HEP-Flury) strain—with that of the original HEP strain. The original HEP strain exhibited higher titer than rHEP and a single substitution at position 80 in the matrix (M) protein M(D80N) after incubation in MNA cells, which was absent in rHEP. In vivo, intracerebral inoculation of the rHEP-M(D80N) strain with this substitution resulted in enhanced viral growth in the mouse brain and a significant loss of body weight in the adult mice. The number of viral antigen-positive cells in the brains of adult mice inoculated with the rHEP-M(D80N) strain was significantly higher than that with the rHEP strain at 5 days post-inoculation. Our findings demonstrate that a single amino acid substitution in the M protein M(D80N) is associated with neurovirulence in mice owing to adaptation to mouse neuronal cells. Full article
(This article belongs to the Special Issue The World of Rhabdoviruses)
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26 pages, 5912 KiB  
Article
The Current Status and Future Prospects of KAGRA, the Large-Scale Cryogenic Gravitational Wave Telescope Built in the Kamioka Underground
by Homare Abe, Tomotada Akutsu, Masaki Ando, Akito Araya, Naoki Aritomi, Hideki Asada, Yoichi Aso, Sangwook Bae, Rishabh Bajpai, Kipp Cannon, Zhoujian Cao, Eleonora Capocasa, Man Leong Chan, Dan Chen, Yi-Ru Chen, Marc Eisenmann, Raffaele Flaminio, Heather K. Fong, Yuta Fujikawa, Yuya Fujimoto, I. Putu Wira Hadiputrawan, Sadakazu Haino, Wenbiao Han, Kazuhiro Hayama, Yoshiaki Himemoto, Naoatsu Hirata, Chiaki Hirose, Tsung-Chieh Ho, Bin-Hua Hsieh, He-Feng Hsieh, Chia-Hsuan Hsiung, Hsiang-Yu Huang, Panwei Huang, Yao-Chin Huang, Yun-Jing Huang, David C. Y. Hui, Kohei Inayoshi, Yuki Inoue, Yousuke Itoh, Pil-Jong Jung, Takaaki Kajita, Masahiro Kamiizumi, Nobuyuki Kanda, Takashi Kato, Chunglee Kim, Jaewan Kim, Young-Min Kim, Yuichiro Kobayashi, Kazunori Kohri, Keiko Kokeyama, Albert K. H. Kong, Naoki Koyama, Chihiro Kozakai, Jun’ya Kume, Sachiko Kuroyanagi, Kyujin Kwak, Eunsub Lee, Hyung Won Lee, Ray-Kuang Lee, Matteo Leonardi, Kwan-Lok Li, Pengbo Li, Lupin Chun-Che Lin, Chun-Yu Lin, En-Tzu Lin, Hong-Lin Lin, Guo-Chin Liu, Ling-Wei Luo, Miftahul Ma’arif, Yuta Michimura, Norikatsu Mio, Osamu Miyakawa, Kouseki Miyo, Shinji Miyoki, Nozomi Morisue, Kouji Nakamura, Hiroyuki Nakano, Masayuki Nakano, Tatsuya Narikawa, Lan Nguyen Quynh, Takumi Nishimoto, Atsushi Nishizawa, Yoshihisa Obayashi, Kwangmin Oh, Masatake Ohashi, Tomoya Ohashi, Masashi Ohkawa, Yoshihiro Okutani, Ken-ichi Oohara, Shoichi Oshino, Kuo-Chuan Pan, Alessandro Parisi, June Gyu Park, Fabián E. Peña Arellano, Surojit Saha, Kazuki Sakai, Takahiro Sawada, Yuichiro Sekiguchi, Lijing Shao, Yutaka Shikano, Hirotaka Shimizu, Katsuhiko Shimode, Hisaaki Shinkai, Ayaka Shoda, Kentaro Somiya, Inhyeok Song, Ryosuke Sugimoto, Jishnu Suresh, Takamasa Suzuki, Takanori Suzuki, Toshikazu Suzuki, Hideyuki Tagoshi, Hirotaka Takahashi, Ryutaro Takahashi, Hiroki Takeda, Mei Takeda, Atsushi Taruya, Takayuki Tomaru, Tomonobu Tomura, Lucia Trozzo, Terrence T. L. Tsang, Satoshi Tsuchida, Takuya Tsutsui, Darkhan Tuyenbayev, Nami Uchikata, Takashi Uchiyama, Tomoyuki Uehara, Koh Ueno, Takafumi Ushiba, Maurice H. P. M. van Putten, Tatsuki Washimi, Chien-Ming Wu, Hsun-Chung Wu, Tomohiro Yamada, Kazuhiro Yamamoto, Takahiro Yamamoto, Ryo Yamazaki, Shu-Wei Yeh, Jun’ichi Yokoyama, Takaaki Yokozawa, Hirotaka Yuzurihara, Simon Zeidler and Yuhang Zhaoadd Show full author list remove Hide full author list
Galaxies 2022, 10(3), 63; https://doi.org/10.3390/galaxies10030063 - 26 Apr 2022
Cited by 26 | Viewed by 8661
Abstract
KAGRA is a gravitational-wave (GW) detector constructed in Japan with two unique key features: It was constructed underground, and the test-mass mirrors are cooled to cryogenic temperatures. These features are not included in other kilometer-scale detectors but will be adopted in future detectors [...] Read more.
KAGRA is a gravitational-wave (GW) detector constructed in Japan with two unique key features: It was constructed underground, and the test-mass mirrors are cooled to cryogenic temperatures. These features are not included in other kilometer-scale detectors but will be adopted in future detectors such as the Einstein Telescope. KAGRA performed its first joint observation run with GEO600 in 2020. In this observation, the sensitivity of KAGRA to GWs was inferior to that of other kilometer-scale detectors such as LIGO and Virgo. However, further upgrades to the detector are ongoing to reach the sensitivity for detecting GWs in the next observation run, which is scheduled for 2022. In this article, the current situation, sensitivity, and future perspectives are reviewed. Full article
(This article belongs to the Special Issue Present and Future of Gravitational Wave Astronomy)
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