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Authors = Xianbin Zhong

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13 pages, 135 KiB  
Article
Stereoselective Syntheses of Fluorescent Non-Natural Aromatic Amino Acids Based on Asymmetric Michael Additions
by Heru Chen, Xianbin Zhong and Jin Wei
Molecules 2007, 12(5), 1170-1182; https://doi.org/10.3390/12051170 - 26 May 2007
Cited by 11 | Viewed by 11689
Abstract
Four fluorescent non-natural aromatic amino acids have been synthesized based on a key stereoselective Michael addition reaction. S-1-Phenylethylamine was employed as both the source of amine and the stereoselectivity controller. The overall yields were moderate (30-50%). Fluorescent properties of some of the fluorophores [...] Read more.
Four fluorescent non-natural aromatic amino acids have been synthesized based on a key stereoselective Michael addition reaction. S-1-Phenylethylamine was employed as both the source of amine and the stereoselectivity controller. The overall yields were moderate (30-50%). Fluorescent properties of some of the fluorophores were also investigated. It was found that compounds with a dimethylamino group bonded to the aromatic ring display intramolecular charge transfer fluorescence. Full article
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