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Authors = Sevim Rollas

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30 pages, 194 KiB  
Review
Biological Activities of Hydrazone Derivatives
by Sevim Rollas and S. Güniz Küçükgüzel
Molecules 2007, 12(8), 1910-1939; https://doi.org/10.3390/12081910 - 17 Aug 2007
Cited by 1152 | Viewed by 39721
Abstract
There has been considerable interest in the development of novel compounds with anticonvulsant, antidepressant, analgesic, antiinflammatory, antiplatelet, antimalarial, antimicrobial, antimycobacterial, antitumoral, vasodilator, antiviral and antischistosomiasis activities. Hydrazones possessing an azometine -NHN=CH- proton constitute an important class of compounds for new drug development. Therefore, [...] Read more.
There has been considerable interest in the development of novel compounds with anticonvulsant, antidepressant, analgesic, antiinflammatory, antiplatelet, antimalarial, antimicrobial, antimycobacterial, antitumoral, vasodilator, antiviral and antischistosomiasis activities. Hydrazones possessing an azometine -NHN=CH- proton constitute an important class of compounds for new drug development. Therefore, many researchers have synthesized these compounds as target structures and evaluated their biological activities. These observations have been guiding for the development of new hydrazones that possess varied biological activities. Full article
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