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Authors = Maru Ando

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10 pages, 2380 KiB  
Communication
Janus Hydrogel Microbeads for Glucose Sensing with pH Calibration
by Maru Ando, Mio Tsuchiya, Shun Itai, Tomomi Murayama, Yuta Kurashina, Yun Jung Heo and Hiroaki Onoe
Sensors 2021, 21(14), 4829; https://doi.org/10.3390/s21144829 - 15 Jul 2021
Cited by 12 | Viewed by 5637
Abstract
We present fluorescent Janus hydrogel microbeads for continuous glucose sensing with pH calibration. The Janus hydrogel microbeads, that consist of fluorescent glucose and pH sensors, were fabricated with a UV-assisted centrifugal microfluidic device. The microbead can calibrate the pH values of its surroundings [...] Read more.
We present fluorescent Janus hydrogel microbeads for continuous glucose sensing with pH calibration. The Janus hydrogel microbeads, that consist of fluorescent glucose and pH sensors, were fabricated with a UV-assisted centrifugal microfluidic device. The microbead can calibrate the pH values of its surroundings and enables accurate measurements of glucose within various pH conditions. As a proof of concept, we succeeded in obtaining the accurate value of glucose concentration in a body-fluid-like sample solution. We believe that our fluorescent microbeads, with pH calibration capability, could be applied to fully implantable sensors for continuous glucose monitoring. Full article
(This article belongs to the Section Biomedical Sensors)
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