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Authors = Daniel GRANČAI

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1 pages, 150 KiB  
Addendum
Addendum: Šarić-Kundalić, B.; Fialová, S.; Dobeš, C.; Ölzant, S.; Tekeľová, D.; Grančai, D.; Reznicek, G.; Saukel, J. Multivariate Numerical Taxonomy of Mentha Species, Hybrids, Varieties and Cultivars. Sci. Pharm. 2009, 77, 851–876
by Broza Šarić-Kundalić, Silvia Fialová, Christoph Dobeš, Silvester Ölzant, Daniela Tekeľová, Daniel Grančai, Gottfried Reznicek and Johannes Saukel
Sci. Pharm. 2016, 84(4), 752; https://doi.org/10.3390/scipharm84040752 - 2 Dec 2016
Cited by 2 | Viewed by 2802
Abstract
In the published paper [1], the following plant species are listed: Mentha longifolia var. lavanduliodora, Mentha spicata and Mentha spicata var. crispa.[...] Full article
7 pages, 394 KiB  
Communication
Antiproliferative Activities of Water Infusions from Leaves of Five Cornus L. Species
by Vladimír Forman, Mária Haladová, Daniel Grančai and Mária Ficková
Molecules 2015, 20(12), 22546-22552; https://doi.org/10.3390/molecules201219786 - 16 Dec 2015
Cited by 25 | Viewed by 5329
Abstract
Cornaceae plants are known for their edible berries, and their leaves are used as tea. In the present study aqueous leaf extracts from Cornus mas (CM), C. alba (CA), C. flaviramea (CF), C. kousa (CK), and C. officinalis (CO) were tested for their [...] Read more.
Cornaceae plants are known for their edible berries, and their leaves are used as tea. In the present study aqueous leaf extracts from Cornus mas (CM), C. alba (CA), C. flaviramea (CF), C. kousa (CK), and C. officinalis (CO) were tested for their antiproliferative activity in human breast cancer cells (MCF-7). Dose- (50–750 µg/mL) and time (24, 48, 72 h)-dependent antiproliferative effects were measured by WST-1, and correlated with the content of flavonoids (FL), total hydroxycinnamic derivatives (THD), total polyphenols (TP) and tannins (T). Extracts induced time dependent decreases in cell survival; CA, CO and CM were the most effective (11.2%, 10.3% and 11.1%, after 72 h). The ED50 (effective dose) values were similar for all extracts and times tested. The THD and TP were identical in all samples, while a two-fold higher T content was present in CK and CO, and of FL in CF. The maximal effects (% of surviving cells) negatively correlated with the T and TP levels, and positively with FL and THD. The results demonstrate the significant antiproliferative effects of the tested water extracts in MCF-7 cells, in which CA, CO and CM are the most effective; and the effectiveness is related to the T and TP contents. Full article
(This article belongs to the Section Natural Products Chemistry)
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26 pages, 2002 KiB  
Article
Multivariate Numerical Taxonomy of Mentha Species, Hybrids, Varieties and Cultivars
by Broza ŠARIĆ-KUNDALIĆ, Silvia FIALOVÁ, Christoph DOBEŠ, Silvester ÖLZANT, Daniela TEKEĽOVÁ, Daniel GRANČAI, Gottfried REZNICEK and Johannes SAUKEL
Sci. Pharm. 2009, 77(4), 851-876; https://doi.org/10.3797/scipharm.0905-10 - 29 Oct 2009
Cited by 71 | Viewed by 4719
Abstract
A taxonomic study into the anatomical, morphological and phytochemical differentiation of the genus Mentha L (Lamiaceae) in Bosnia & Hercegovina and Slovakia is presented. Following a population-based approach and using hierarchical cluster analyses the following basic species and hybrids corresponding to exclusive branches, [...] Read more.
A taxonomic study into the anatomical, morphological and phytochemical differentiation of the genus Mentha L (Lamiaceae) in Bosnia & Hercegovina and Slovakia is presented. Following a population-based approach and using hierarchical cluster analyses the following basic species and hybrids corresponding to exclusive branches, i.e. groups, in the constructed hierarchies were recognized: Mentha aquatica, M. spicata, M. arvensis, M. longifolia, M. rotundifolia, M. × piperita, M. × villosa, M. × verticillata, M. × gentillis, M. × gracilis and M. pulegium. These groups were independently found by separate analyses of the sampled anatomical and morphological variation. In contrast, these anatomically and morphologically defined species exhibited a high level of phytochemical polymorphism which was largely inconsistent with the hierarchical classification. Among the analysed characters, the inflorescence type, dentation of the leaf margin, hair density, the type of capitate glandular hairs, and the main containing compound in essential oil proved most useful for the discrimination of taxa. However, most of the observed traits were not exclusive to a particular species and only the combined consideration of traits revealed coherent taxonomic groups. Basic species and hybrids are described in detail based on the anatomical, morphological and phytochemical characters used for their definition. The performed cluster analysis finally supported hypotheses on the parentage of some of the studied hybrids. Full article
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