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Authors = Charlene Y. C. Chau

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20 pages, 2024 KiB  
Review
Optimal Timing of External Ventricular Drainage after Severe Traumatic Brain Injury: A Systematic Review
by Charlene Y. C. Chau, Saniya Mediratta, Mikel A. McKie, Barbara Gregson, Selma Tulu, Ari Ercole, Davi J. F. Solla, Wellingson S. Paiva, Peter J. Hutchinson and Angelos G. Kolias
J. Clin. Med. 2020, 9(6), 1996; https://doi.org/10.3390/jcm9061996 - 25 Jun 2020
Cited by 23 | Viewed by 7197
Abstract
External ventricular drainage (EVD) may be used for therapeutic cerebrospinal fluid (CSF) drainage to control intracranial pressure (ICP) after traumatic brain injury (TBI). However, there is currently uncertainty regarding the optimal timing for EVD insertion. This study aims to compare patient outcomes for [...] Read more.
External ventricular drainage (EVD) may be used for therapeutic cerebrospinal fluid (CSF) drainage to control intracranial pressure (ICP) after traumatic brain injury (TBI). However, there is currently uncertainty regarding the optimal timing for EVD insertion. This study aims to compare patient outcomes for patients with early and late EVD insertion. Following the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines, MEDLINE/EMBASE/Scopus/Web of Science/Cochrane Central Register of Controlled Trials were searched for published literature involving at least 10 severe TBI (sTBI) patients from their inception date to December 2019. Outcomes assessed were mortality, functional outcome, ICP control, length of stay, therapy intensity level, and complications. Twenty-one studies comprising 4542 sTBI patients with an EVD were included; 19 of the studies included patients with an early EVD, and two studies had late EVD placements. The limited number of studies, small sample sizes, imbalance in baseline characteristics between the groups and poor methodological quality have limited the scope of our analysis. We present the descriptive statistics highlighting the current conflicting data and the overall lack of reliable research into the optimal timing of EVD. There is a clear need for high quality comparisons of early vs. late EVD insertion on patient outcomes in sTBI. Full article
(This article belongs to the Special Issue Traumatic Brain Injury: Recent Developments and Emerging Trends)
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23 pages, 10600 KiB  
Review
The Evolution of the Role of External Ventricular Drainage in Traumatic Brain Injury
by Charlene Y. C. Chau, Claudia L. Craven, Andres M. Rubiano, Hadie Adams, Selma Tülü, Marek Czosnyka, Franco Servadei, Ari Ercole, Peter J. Hutchinson and Angelos G. Kolias
J. Clin. Med. 2019, 8(9), 1422; https://doi.org/10.3390/jcm8091422 - 10 Sep 2019
Cited by 48 | Viewed by 13911
Abstract
External ventricular drains (EVDs) are commonly used in neurosurgery in different conditions but frequently in the management of traumatic brain injury (TBI) to monitor and/or control intracranial pressure (ICP) by diverting cerebrospinal fluid (CSF). Their clinical effectiveness, when used as a therapeutic ICP-lowering [...] Read more.
External ventricular drains (EVDs) are commonly used in neurosurgery in different conditions but frequently in the management of traumatic brain injury (TBI) to monitor and/or control intracranial pressure (ICP) by diverting cerebrospinal fluid (CSF). Their clinical effectiveness, when used as a therapeutic ICP-lowering procedure in contemporary practice, remains unclear. No consensus has been reached regarding the drainage strategy and optimal timing of insertion. We review the literature on EVDs in the setting of TBI, discussing its clinical indications, surgical technique, complications, clinical outcomes, and economic considerations. Full article
(This article belongs to the Section Clinical Neurology)
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