We are pleased to announce that Prof. Dr. Fabio Di Domenico has been appointed Section Editor-in-Chief of “Molecular Medicine” in Biomolecules (ISSN: 2218-273X).

Prof. Dr. Fabio Di Domenico is a Full Professor of biochemistry at the Faculty of Pharmacy and Medicine of Sapienza University of Rome, Italy. His research primarily focuses on investigating how defective proteostasis contributes to the development of Alzheimer’s-like dementia, aiming to identify novel therapeutic strategies to improve cognitive function. During his former studies at the University of Kentucky in Prof. D. Allan Butterfield’s laboratory, he played a key role in establishing redox proteomics techniques, which helped uncover the role of oxidative stress and impaired protein degradation systems in the onset and progression of Alzheimer’s-like dementia. Prof. Fabio Di Domenico’s recent work has revealed that the chronic activation of the unfolded protein response significantly influences the progression of Alzheimer’s-like dementia, both in the general population and in individuals with Down syndrome. These findings have paved the way for research assessing how various compounds can prevent or treat cognitive decline. Additionally, his research explores the role of disrupted O-GlcNAc cycling and metabolic dysfunctions in the development of Alzheimer’s-related pathological features. Prof. Fabio Di Domenico has published over 115 articles in prestigious international peer-reviewed journals and has an H-index above 50.

The following is a short Q&A with Prof. Dr. Fabio Di Domenico, who shared his vision for the journal with us, as well as his views of the research area and open access publishing:

1. What aspects of the journal attracted and motivated you to become its Section Editor-in-Chief?
I was thrilled by the journal and its dedicated Section focusing on natural and bio-inspired molecules, as it provides an ideal platform for conducting research spanning various areas, ranging from fundamental biomedical science and pharmacology studies to clinical investigations.

2. What is your vision for this Section?
This Section aims to serve as an excellent platform for biologists, pharmacists, and clinicians to showcase their cutting-edge research on natural and bio-inspired molecules, thereby expanding the frontiers of the field.

3. What does the future of this field of research look like?
Research on natural and bio-inspired molecules/compounds is a highly dynamic field, encompassing a wide range of investigations. It involves understanding the intricate mechanisms by which these remarkable structural molecules interact with our biological systems, as well as exploring how the body responds to them as potential prototype drugs. This field explores the sources, biological effects, chemical properties, and diagnostic/therapeutic applications of natural and bio-inspired molecules. Active involvement in this field is truly captivating, and the journal’s Section “Natural and Bio-inspired Molecules” serves as a vital platform for researchers worldwide, facilitating effective communication and collaboration among experts in the field.

4. Do you have any suggestions for young researchers in this field?
Research is a journey of continuous learning and growth. Be persistent, curious, and open to new ideas and approaches. Young researchers should always stay updated and collaborate with others to keep themselves aware of the latest advancements, trends, and publications in their research area. In addition, attend conferences and join professional networks to stay connected with the research community to seek fruitful collaborations with other researchers, both within and outside your institution. In my experience, collaborations provide opportunities for exchanging knowledge, learning from others' expertise, and conducting interdisciplinary research.

5. What do you think of the development of open access in the publishing field?
It is an essential trend in the field of publication. We can continue working together through open access to ensure our peer-reviewed research serves the scientific community.

We warmly welcome Prof. Dr. Fabio Di Domenico as the Section Editor-in-Chief of “Molecular Medicine”, and we look forward to him leading Biomolecules to achieve many more milestones.