Health-Promoting Effects of Goji Berries (Lycium barbarum): A Literature Overview †
Abstract
:1. Introduction
2. Methods
- Population (P): healthy individuals or patients diagnosed with any disease according to internationally recognized clinical standards.
- Intervention (I): consumption of Goji berries and their derivatives (such as fruit juice, dried products, and phytotherapeutic extracts containing polysaccharides) for any duration.
- Comparison (C): no consumption of Goji berries and their derivatives.
- Outcomes (O): any health-related parameter, including changes in metabolic indices, vital signs, body weight, oxidative stress status, and quality of life.
- Study design (S): meta-analyses of clinical studies.
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Studies (Sample Size)—Population | Intervention: Goji Berries | Health Outcomes | Pooled Analysis | Review Guidelines | Year | Ref. |
---|---|---|---|---|---|---|
4 studies (n = 161)—healthy subjects |
| Fatigue | OR = 3.51 [95% CI: 1.45; 8.48] (*) | - | 2012 | [8] |
Dizziness | OR = 2.65 [95% CI: 1.15; 6.12] (*) | |||||
Sleep | OR = 3.23 [95% CI: 1.23; 8.47] (*) | |||||
7 studies (n = 548)—healthy subjects or patients with DM |
| Triglycerides | MD = −17.7 mg/dL [95% CI: −40.7; 4.4] | PRISMA | 2017 | [10] |
Total cholesterol | MD = −11.6 mg/dL [95% CI: −29.0; 5.8] | |||||
Fasting glucose | MD = −6.5 mg/dL [95% CI: −11.3; −1.8] (*) | |||||
SBP | MD = 0.02 mmHg [95% CI: −4.26; 4.30] | |||||
DBP | MD = −1.59 mmHg [95% CI: −4.57; 1.40] | |||||
Body weight | MD = 0.13 kg [95% CI: −1.87; 2.14] | |||||
10 studies (n = 547)—healthy subjects or patients with DM, metabolic syndrome, or hypercholesterolemia |
| Triglycerides | MD = −12.4 mg/dL [95% CI: −16.8; −8.0] (*) | PRISMA | 2022 | [9] |
HDL cholesterol | MD = 2.3 mg/dL [95% CI: 0.8; 3.5] (*) | |||||
LDL cholesterol | MD = 0.00 mg/dL [95% CI: −14.3; 13.9] | |||||
SBP | MD = 0.3 mmHg [95% CI: −1.5; 2.0] | |||||
DPB | MD = − 0.6 mmHg [95% CI: −1.7; 0.5] | |||||
Oxidative stress status (blood MDA) | g = −1.45 [95% CI: −2.75; −0.16] (*) | |||||
6 studies (n = 459)—healthy subjects or patients with DM |
| Triglycerides | SMD = −0.46 [95% CI: −0.68; −0.23] (*) | - | 2022 | [11] |
Total cholesterol | SMD = −0.42 [95% CI: −0.95; 0.12] | |||||
HDL cholesterol | SMD = 1.11 [95% CI: 0.51; 1.72] (*) | |||||
LDL cholesterol | SMD = −0.53 [95% CI: −0.90; −0.16] (*) | |||||
Fasting glucose | SMD = −0.71 [95% CI: −1.37; −0.04] (*) | |||||
5 studies (n = 259)—healthy subjects or patients with DM or metabolic syndrome |
| Triglycerides | MD = −12.4 mg/dL, [95% CI: −17.7; −7.1] (*) | PRISMA | 2023 | [12] |
HDL cholesterol | MD = 2.7 mg/dL, [95% CI: 0.4; 5.0] (*) | |||||
LDL cholesterol | MD = −8.1 mg/dL, [95% CI: −34.4; 17.8] | |||||
Total cholesterol | MD = −4.3 mg/dL, [95% CI: −22.8; 14.3] |
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Antonelli, M.; Donelli, D. Health-Promoting Effects of Goji Berries (Lycium barbarum): A Literature Overview. Biol. Life Sci. Forum 2024, 40, 1. https://doi.org/10.3390/blsf2024040001
Antonelli M, Donelli D. Health-Promoting Effects of Goji Berries (Lycium barbarum): A Literature Overview. Biology and Life Sciences Forum. 2024; 40(1):1. https://doi.org/10.3390/blsf2024040001
Chicago/Turabian StyleAntonelli, Michele, and Davide Donelli. 2024. "Health-Promoting Effects of Goji Berries (Lycium barbarum): A Literature Overview" Biology and Life Sciences Forum 40, no. 1: 1. https://doi.org/10.3390/blsf2024040001
APA StyleAntonelli, M., & Donelli, D. (2024). Health-Promoting Effects of Goji Berries (Lycium barbarum): A Literature Overview. Biology and Life Sciences Forum, 40(1), 1. https://doi.org/10.3390/blsf2024040001