Rotavirus Gastroenteritis in Children Less than Five Years of Age in Primary Care Settings in Bulgaria: An Observational Study
Abstract
Background
Methods
Study Design
Study Population and Case Definition
Data Collection
Diagnosis of RV
Statistical Analysis
Results
Demographic Characteristics
Proportion of RVGE Cases
| RV-Positive N = 159 | RV-Negative N = 465 | |||||
|---|---|---|---|---|---|---|
| Age (months) | Severity | n | % | n | % | p-Values |
| Mild (1-6) | 0 | 0.0 | 9 | 20.0 | ||
| 0-5 | Moderate (7-10) | 1 | 16.7 | 19 | 42.2 | 0.160 |
| Severe (≥11) | 5 | 83.3 | 17 | 37.8 | ||
| Mild (1-6) | 1 | 4.2 | 10 | 14.3 | ||
| 6-11 | Moderate (7-10) | 2 | 8.3 | 26 | 37.1 | 0.003 |
| Severe (≥11) | 21 | 87.5 | 34 | 48.6 | ||
| Mild (1-6) | 1 | 2.1 | 18 | 12.1 | ||
| 12-23 | Moderate (7-10) | 9 | 18.8 | 45 | 30.2 | 0.017 |
| Severe (≥11) | 38 | 79.2 | 86 | 57.7 | ||
| Mild (1-6) | 5 | 6.2 | 23 | 11.4 | ||
| 24-59 | Moderate (7-10) | 10 | 12.3 | 61 | 30.3 | 0.001 |
| Severe (≥11) | 66 | 81.5 | 117 | 58.2 | ||
| Mild (1-6) | 1 | 3.3 | 19 | 16.5 | ||
| 0-11 | Moderate (7-10) | 3 | 10.0 | 45 | 39.1 | < 0.001 |
| Severe (≥11) | 26 | 86.7 | 51 | 4.3 | ||
| Mild (1-6) | 6 | 4.7 | 41 | 11.7 | ||
| 12-59 | Moderate (7-10) | 19 | 14.7 | 106 | 30.3 | < 0.001 |
| Severe (≥11) | 104 | 80.6 | 203 | 58.0 | ||
| Mild (1-6) | 7 | 4.4 | 60 | 12.9 | ||
| Overall | Moderate (7-10) | 22 | 13.8 | 151 | 32.5 | < 0.001 |
| Severe (≥11) | 130 | 81.8 | 254 | 54.6 | ||
Proportion of Patients Hospitalized for AGE
Seasonal Distribution of RVGE
Discussion
Conclusions
Authors’ Contributions Statement
Funding
Acknowledgments
Conflicts of Interest
References
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| RV-Positive N = 159 | RV-Negative N = 465 | |||||||
|---|---|---|---|---|---|---|---|---|
| Age (months) | N | n | % | 95% CI | N | n | % | 95% CI |
| 0-5 | 6 | 1 | 16.7 | 0.4-64.1 | 45 | 2 | 4.4 | 0.5-15.1 |
| 6-11 | 24 | 7 | 29.2 | 12.6-51.1 | 70 | 1 | 1.1 | 0.0-7.7 |
| 12-23 | 48 | 11 | 22.9 | 12.0-37.3 | 149 | 1 | 0.7 | 0.0-3.7 |
| 24-59 | 81 | 13 | 16.0 | 8.8-25.9 | 201 | 3 | 1.5 | 0.3-4.3 |
| All | 159 | 32 | 20.1 | 14.2-27.2 | 465 | 7 | 1.5 | 0.6-3.1 |
© GERMS 2016.
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Tiholova, M.; Gopala, K.; Berberova, M.; Strokova-Stoilova, M.; Tafalla, M. Rotavirus Gastroenteritis in Children Less than Five Years of Age in Primary Care Settings in Bulgaria: An Observational Study. GERMS 2016, 6, 97-105. https://doi.org/10.11599/germs.2016.1095
Tiholova M, Gopala K, Berberova M, Strokova-Stoilova M, Tafalla M. Rotavirus Gastroenteritis in Children Less than Five Years of Age in Primary Care Settings in Bulgaria: An Observational Study. GERMS. 2016; 6(3):97-105. https://doi.org/10.11599/germs.2016.1095
Chicago/Turabian StyleTiholova, Mayda, Kusuma Gopala, Magda Berberova, Margarita Strokova-Stoilova, and Monica Tafalla. 2016. "Rotavirus Gastroenteritis in Children Less than Five Years of Age in Primary Care Settings in Bulgaria: An Observational Study" GERMS 6, no. 3: 97-105. https://doi.org/10.11599/germs.2016.1095
APA StyleTiholova, M., Gopala, K., Berberova, M., Strokova-Stoilova, M., & Tafalla, M. (2016). Rotavirus Gastroenteritis in Children Less than Five Years of Age in Primary Care Settings in Bulgaria: An Observational Study. GERMS, 6(3), 97-105. https://doi.org/10.11599/germs.2016.1095

