Next Article in Journal
Verifying the Real Estimates of COVID-19 Deaths in Africa
Previous Article in Journal
Bulging Fontanel During a Measles Infection
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
GERMS
Volume 10
Issue 4
10.18683/germs.2020.1232
germs-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Case Report

Fulminant Cryptococcal Meningoencephalitis After Successful Treatment of Primary Cutaneous Cryptococcosis

by
Iordanis Romiopoulos
1,
Zoi Dorothea Pana
1,
Athina Pyrpasopoulou
2,
Ioanna Linardou
3,
Eugenia Avdelidi
4,
Maria Sidiropoulou
5,
Eleni Chatzidrosou
6,
Dimitrios Ioannides
7,
Asterios Karagiannis
3 and
Emmanuel Roilides
1,*
1
Infectious Diseases Unit, Hippokration Hospital, 54642 Thessaloniki, Greece
2
Infectious Diseases Unit, 2nd Propedeutic Department of Internal Medicine, Hippokration Hospital, 54642 Thessaloniki, Greece
3
2nd Propedeutic Department of Internal Medicine, Hippokration Hospital, 54642 Thessaloniki, Greece
4
Neurology Department, Hippokration Hospital, 54642 Thessaloniki, Greece
5
Radiology Department, Hippokration Hospital, 54642 Thessaloniki, Greece
6
Microbiology Department, Hippokration Hospital, 54642 Thessaloniki, Greece
7
A’ Department for Skin and Venereal Diseases, Hippokration Hospital, 54642 Thessaloniki, Greece
*
Author to whom correspondence should be addressed.
GERMS 2020, 10(4), 388-391; https://doi.org/10.18683/germs.2020.1232
Submission received: 1 May 2020 / Revised: 3 August 2020 / Accepted: 17 August 2020 / Published: 28 December 2020
Versions Notes

Abstract

Introduction: Cryptococcal meningoencephalitis is a life-threatening disease affecting mainly immunocompromised hosts. Case report: We present a case of a 64-year-old immunocompetent patient, who initially developed a traumatic scalp skin infection due to Cryptococcus neoformans. The patient received oral fluconazole and subsequently liposomal amphotericin B due to the development of resistance with resolution of the infection. Two years later, during chemotherapy for newly diagnosed gastric and lung cancer, he developed fulminant cryptococcal meningoencephalitis, which did not respond to liposomal amphotericin B and flucytosine. Conclusions: To our knowledge, this is the first case of fulminant cryptococcal meningoencephalitis following long latency after adequately treated primary cutaneous infection.
Keywords: Cryptococcus; meningitis; skin infection Cryptococcus; meningitis; skin infection

Share and Cite

MDPI and ACS Style

Romiopoulos, I.; Pana, Z.D.; Pyrpasopoulou, A.; Linardou, I.; Avdelidi, E.; Sidiropoulou, M.; Chatzidrosou, E.; Ioannides, D.; Karagiannis, A.; Roilides, E. Fulminant Cryptococcal Meningoencephalitis After Successful Treatment of Primary Cutaneous Cryptococcosis. GERMS 2020, 10, 388-391. https://doi.org/10.18683/germs.2020.1232

AMA Style

Romiopoulos I, Pana ZD, Pyrpasopoulou A, Linardou I, Avdelidi E, Sidiropoulou M, Chatzidrosou E, Ioannides D, Karagiannis A, Roilides E. Fulminant Cryptococcal Meningoencephalitis After Successful Treatment of Primary Cutaneous Cryptococcosis. GERMS. 2020; 10(4):388-391. https://doi.org/10.18683/germs.2020.1232

Chicago/Turabian Style

Romiopoulos, Iordanis, Zoi Dorothea Pana, Athina Pyrpasopoulou, Ioanna Linardou, Eugenia Avdelidi, Maria Sidiropoulou, Eleni Chatzidrosou, Dimitrios Ioannides, Asterios Karagiannis, and Emmanuel Roilides. 2020. "Fulminant Cryptococcal Meningoencephalitis After Successful Treatment of Primary Cutaneous Cryptococcosis" GERMS 10, no. 4: 388-391. https://doi.org/10.18683/germs.2020.1232

APA Style

Romiopoulos, I., Pana, Z. D., Pyrpasopoulou, A., Linardou, I., Avdelidi, E., Sidiropoulou, M., Chatzidrosou, E., Ioannides, D., Karagiannis, A., & Roilides, E. (2020). Fulminant Cryptococcal Meningoencephalitis After Successful Treatment of Primary Cutaneous Cryptococcosis. GERMS, 10(4), 388-391. https://doi.org/10.18683/germs.2020.1232

Article Metrics

Back to TopTop