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Open AccessReview

Relapsing Polychondritis: An Updated Review

Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, 98125 Messina, Italy
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Biomedicines 2018, 6(3), 84; https://doi.org/10.3390/biomedicines6030084
Received: 30 May 2018 / Revised: 23 July 2018 / Accepted: 25 July 2018 / Published: 2 August 2018
Relapsing polychondritis is an immune-mediated systemic disease characterized by recurrent episodes of inflammation of cartilaginous and proteoglycan-rich tissues, resulting in progressive anatomical deformation and functional impairment of the involved structures. Auricular and nasal chondritis and/or polyarthritis represent the most common clinical features, but potentially all types of cartilage may be involved. Because of the pleomorphic nature of the disease, with non-specific symptoms at the onset, the diagnosis of relapsing polychondritis is often delayed. In this review article we provide a comprehensive look into clinical presentation, laboratory and instrumental investigations, diagnostic criteria, and therapeutic options. View Full-Text
Keywords: relapsing polychondritis; auricular chondritis; systemic autoimmune disease; cartilage; anti-type II collagen antibodies relapsing polychondritis; auricular chondritis; systemic autoimmune disease; cartilage; anti-type II collagen antibodies
MDPI and ACS Style

Borgia, F.; Giuffrida, R.; Guarneri, F.; Cannavò, S.P. Relapsing Polychondritis: An Updated Review. Biomedicines 2018, 6, 84.

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