Special Issue "Antioxidants 2012"

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A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: closed (30 November 2012)

Special Issue Editor

Guest Editor
Dr. Dejian Huang
Food Science & Technology Programme, c/o Department of Chemistry, 3 Science Drive 3, Faculty of Science, National University of Singapore, 117543 Singapore
Website: http://www.fst.nus.edu.sg/OurPeople/HuangDJ.htm
E-Mail: chmhdj@nus.edu.sg
Phone: +65 6516 8821
Fax: +65 6775 7895
Interests: fabrication of quantum dots; transition metal complex; polyphenolic compounds; antioxidant; pro-oxidant activity

Special Issue Information

Dear Colleagues,

Mounting evidence suggests that oxidative stress is the causative factor for chronic diseases including cardiovascular diseases, cancer, diabetes, neurodegenerative diseases and ageing. Preventing these chronic diseases through antioxidants (or radical scavengers) has been a very attractive idea as evidenced by the large amount of scholarly articles published. As a result, the notion that dietary antioxidant are beneficial to our health is widely accepted in general public. Scientifically, the action mechanisms of antioxidant are much more complex and remain to be a hotly pursued research field.  Antioxidants may work as oxidase (e.g. lipoxygenases and cyclooxygenase) inhibitor, transition metal chelators (preventing Fenton reaction), and scavengers of wide range of biologically relevant reactive oxygen species including superoxide, peroxyl radicals, hypochlorite, peroxynitrite and nitrogen dioxide, and singlet oxygen. In this special issue on “antioxidants” the contributions may cover chemical, cell line, and in vivo protocols or methods in evaluation of antioxidant activity against  oxidants or oxidative stress; chemical synthesis of novel antioxidant compounds and their activity and action mechanisms; extraction, isolation and structural characterization of dietary antioxidants from natural resources; activity and mechanisms of antioxidants in chemical, food, and biological models; replacement of synthetic radical scavengers (e.g. BHT) by naturally occurring antioxidants; digestion, absorption, and metabolism of dietary antioxidants in animal model and human study; efficacy of antioxidants in mitigating oxidative stress status in human clinical trials.

Dr. Dejian Huang
Guest Editor

Keywords

•    bioactivity
•    antioxidants
•    radical scavengers
•    analytical methods
•    structure elucidation
•    mechanism of action
•    oxidative stress
•    natural products

Published Papers (27 papers)

Molecules 2013, 18(6), 6128-6141; doi:10.3390/molecules18066128
Received: 4 March 2013; in revised form: 20 May 2013 / Accepted: 20 May 2013 / Published: 23 May 2013
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Molecules 2013, 18(3), 3467-3478; doi:10.3390/molecules18033467
Received: 23 January 2013; in revised form: 31 January 2013 / Accepted: 14 March 2013 / Published: 18 March 2013
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Molecules 2013, 18(3), 3410-3426; doi:10.3390/molecules18033410
Received: 30 November 2012; in revised form: 8 March 2013 / Accepted: 12 March 2013 / Published: 14 March 2013
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Molecules 2013, 18(3), 3241-3249; doi:10.3390/molecules18033241
Received: 31 December 2012; in revised form: 16 January 2013 / Accepted: 6 March 2013 / Published: 13 March 2013
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Molecules 2013, 18(2), 2005-2017; doi:10.3390/molecules18022005
Received: 23 November 2012; in revised form: 28 January 2013 / Accepted: 31 January 2013 / Published: 5 February 2013
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Molecules 2013, 18(2), 1811-1818; doi:10.3390/molecules18021811
Received: 28 November 2012; in revised form: 10 January 2013 / Accepted: 15 January 2013 / Published: 30 January 2013
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Molecules 2013, 18(1), 1128-1137; doi:10.3390/molecules18011128
Received: 29 November 2012; in revised form: 4 January 2013 / Accepted: 11 January 2013 / Published: 16 January 2013
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Molecules 2013, 18(1), 690-700; doi:10.3390/molecules18010690
Received: 23 November 2012; in revised form: 14 December 2012 / Accepted: 28 December 2012 / Published: 4 January 2013
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Molecules 2013, 18(1), 178-189; doi:10.3390/molecules18010178
Received: 26 October 2012; in revised form: 16 November 2012 / Accepted: 20 November 2012 / Published: 24 December 2012
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Molecules 2013, 18(1), 167-177; doi:10.3390/molecules18010167
Received: 22 November 2012; in revised form: 10 December 2012 / Accepted: 19 December 2012 / Published: 24 December 2012
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Molecules 2012, 17(12), 14637-14650; doi:10.3390/molecules171214637
Received: 25 October 2012; in revised form: 9 November 2012 / Accepted: 5 December 2012 / Published: 10 December 2012
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Molecules 2012, 17(12), 14602-14624; doi:10.3390/molecules171214602
Received: 16 November 2012; in revised form: 26 November 2012 / Accepted: 5 December 2012 / Published: 7 December 2012
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Molecules 2012, 17(12), 14490-14509; doi:10.3390/molecules171214490
Received: 27 September 2012; in revised form: 26 November 2012 / Accepted: 29 November 2012 / Published: 6 December 2012
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Molecules 2012, 17(12), 14336-14348; doi:10.3390/molecules171214336
Received: 21 September 2012; in revised form: 7 November 2012 / Accepted: 13 November 2012 / Published: 3 December 2012
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Molecules 2012, 17(12), 13769-13786; doi:10.3390/molecules171213769
Received: 11 October 2012; in revised form: 19 November 2012 / Accepted: 20 November 2012 / Published: 22 November 2012
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Molecules 2012, 17(11), 13357-13367; doi:10.3390/molecules171113357
Received: 13 September 2012; in revised form: 26 October 2012 / Accepted: 31 October 2012 / Published: 9 November 2012
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Molecules 2012, 17(11), 12974-12983; doi:10.3390/molecules171112974
Received: 25 September 2012; in revised form: 10 October 2012 / Accepted: 25 October 2012 / Published: 1 November 2012
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Molecules 2012, 17(11), 12851-12867; doi:10.3390/molecules171112851
Received: 27 August 2012; in revised form: 2 September 2012 / Accepted: 21 September 2012 / Published: 1 November 2012
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Molecules 2012, 17(11), 12734-12745; doi:10.3390/molecules171112734
Received: 13 July 2012; in revised form: 18 September 2012 / Accepted: 22 October 2012 / Published: 26 October 2012
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Molecules 2012, 17(10), 12297-12311; doi:10.3390/molecules171012297
Received: 10 September 2012; in revised form: 19 September 2012 / Accepted: 12 October 2012 / Published: 19 October 2012
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Molecules 2012, 17(10), 11897-11919; doi:10.3390/molecules171011897
Received: 15 September 2012; in revised form: 21 September 2012 / Accepted: 7 October 2012 / Published: 9 October 2012
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Molecules 2012, 17(10), 11816-11825; doi:10.3390/molecules171011816
Received: 26 July 2012; in revised form: 28 September 2012 / Accepted: 30 September 2012 / Published: 9 October 2012
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Molecules 2012, 17(10), 11484-11494; doi:10.3390/molecules171011484
Received: 4 July 2012; in revised form: 28 August 2012 / Accepted: 21 September 2012 / Published: 27 September 2012
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Molecules 2012, 17(10), 11421-11434; doi:10.3390/molecules171011421
Received: 7 August 2012; in revised form: 19 September 2012 / Accepted: 20 September 2012 / Published: 26 September 2012
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Molecules 2012, 17(10), 11391-11420; doi:10.3390/molecules171011391
Received: 30 August 2012; in revised form: 12 September 2012 / Accepted: 21 September 2012 / Published: 26 September 2012
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Molecules 2012, 17(9), 10355-10369; doi:10.3390/molecules170910355
Received: 12 June 2012; in revised form: 9 August 2012 / Accepted: 13 August 2012 / Published: 29 August 2012
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Molecules 2012, 17(7), 8037-8055; doi:10.3390/molecules17078037
Received: 21 May 2012; in revised form: 23 June 2012 / Accepted: 2 July 2012 / Published: 4 July 2012
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Last update: 4 March 2014

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