2,087,035 Results Found

Regulation of mRNA 3′ poly(A) tail length plays a central role in post-transcriptional gene regulation by controlling mRNA stability and translational efficiency. Although cytoplasmic polyadenylation has been extensively studied in oocytes and...

Background/Objectives: Topical therapies, primarily imiquimod (IMQ) and 5-fluorouracil (5-FU), have emerged as valuable treatment options in non-melanoma skin cancers (NMSC) due to their facile administration and minimal systemic reactions, especiall...

Primary open-angle glaucoma (POAG) is the leading cause of irreversible blindness worldwide. Intraocular pressure (IOP) is its only validated therapeutic target, yet some patients progress despite controlled IOP, sustaining interest in a vascular con...

Delayed wound healing in diabetes mellitus represents a formidable clinical challenge, characterized by core pathological hallmarks including persistent inflammation, impaired angiogenesis, excessive oxidative stress, and heightened infectivity. Chit...

State-of-the-art vision–language models (VLMs) show emerging reasoning but demand prohibitive computation, limiting deployment in constrained environments. This research addresses this via a dual-phase framework: trace distillation for structur...

Piezo-driven microinjectors have been widely applied in the biomedical field as an effective tool for cell micromanipulation. To improve the survival rate and efficiency of injection, the puncture force and the position of the microinjector should be...

This study investigates the long-term wetting-induced deformation of an unsaturated expansive-soil embankment under seasonal rainfall and drying and evaluates the effects of pile reinforcement. A two-dimensional hydro-mechanical model incorporating t...

The development of efficient visible-light-responsive photocatalysts is essential for the sustainable remediation of water contaminated with persistent organic pollutants. In this work, BiAlO₃ perovskite was investigated as a pristine photocatalyst f...

Background/Objectives: Avacopan-associated liver injury is an emerging safety concern in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), particularly in Japan. We investigated its clinical characteristics and ass...

Anxiety symptoms can affect university students’ educational experiences, highlighting the need for assessment approaches that account for the psychological construct and time frame being measured. This study introduces Affectra, an AI-driven A...

This study examined the association between dead fuel moisture content (DFMC) and wildfire occurrence in Gangwon Province, South Korea, during 2020–2024. Hourly 10-h DFMC, estimated with a Random Forest model at the nearest automatic weather st...

We investigated a class of backward stochastic differential equations with jumps (BSDEJs) characterized by singular generators and nonlinear growth conditions. Specifically, the framework accommodated singular behavior near the origin, together with...

Fusarium wilt of banana is a soil-borne disease caused by Fusarium oxysporum f. sp. cubense tropical race 4 (Foc TR4). This study aimed to identify the Fusarium wilt of banana pathogen in Honghe Prefecture, a low-latitude subtropical region in southe...

The influence of nominal Pt underlayer thickness on in-plane magnetization reversal was investigated in Pt(t)/Co(5 Å)/Pt(5 Å)/CoO(100 Å)/Pt(10 Å) heterostructures deposited on polyethylene terephthalate (PET), with t = 5, 10,...

Plastic pollution is an increasing threat to marine biodiversity, ecosystem functioning, and potentially human health. Addressing marine plastic pollution requires assessment approaches linking environmental and human health within interconnected com...

Macrophages coordinate the transition from tissue injury and inflammation to resolution and repair. Beyond conventional polarization models, their functions depend on context-dependent redox signaling integrated with mitochondrial activity, metabolis...

Lactic acid bacteria (LAB)-derived nanoparticles (NPs) may differ from commercial reference materials in their physicochemical and functional properties. This study evaluated biogenic iron- and silver-based NP preparations and selected commercial cou...

In this study, NbOFFIVE-1-Ni composite gel beads were synthesized via an in situ hydrothermal strategy by incorporating the niobium source precursor into a sodium alginate matrix. The composite beads exhibited a three-dimensional hierarchical structu...

Accurate sensorless speed feedback is essential for compact ultrasonic motor (USM) systems, but physics-based estimators may become inaccurate under nonlinear friction and changing operating conditions, and high-capacity data-driven models are often...

Cartography spans millennia of human civilization. Maps helped humans to interpret and represent the world before even writing was developed. This review examines the evolution of cartographic knowledge from Prehistory to the Middle Ages. It focuses...

AI-assisted reading interfaces often present a few passages from a known scientific document. We evaluated how much annotated evidence remains visible under fixed selection budgets using SciFact and QASPER. Without fine-tuning, we compared leading pa...

High-resolution seismic impedance inversion is important for characterizing reservoir heterogeneity and fine stratigraphic structure, but limited seismic bandwidth and sparse well control hinder high-frequency recovery. We propose a deep learning met...

For coverage optimization in wireless sensor networks (WSNs) with a fixed number of sensor nodes and a fixed sensing radius, the standard Grey Wolf Optimizer (GWO) provides a three-leader search framework, but its conventional position-update mechani...

Background/Objectives: As part of their daily duties, law enforcement officers (LEOs) may be required to undertake physically demanding tasks like pursuing offenders on foot, effecting an arrest, and dragging injured people to safety. Obstacle course...

Background/Objectives: Rituximab has been widely used for the treatment of cancers, and the occurrence of infusion-related reactions (IRRs) is one of the main concerns. Although rituximab-associated IRRs have been well documented, data specifically d...

Recent advances in micronutrient biology have highlighted the pleiotropic roles of vitamins D and K in central nervous system (CNS) health and disease. Beyond their classical functions in calcium homeostasis, both vitamins exhibit regulatory effects...

Vortex-induced-vibration bladeless wind turbines exhibit limited energy-harvesting bandwidth because their aeroelastic response varies with wind speed. This study investigates a tunable turbine incorporating a variable-effective-length clamped–...

The overall performance, pollutant emissions, and operational reliability of gas turbines are strongly influenced by combustor design. However, combustor design remains challenging because of the strong coupling among turbulent flow, fuel–air m...

Heterogeneous electric truck platoons require longitudinal coordination that balances energy consumption, transport efficiency, and safety despite differences in vehicle characteristics. This paper proposes a Distributed Multi-Agent Cooperative Contr...

Background: Sample loss during preparation is one of the issues in unveiling the complexity of the proteome. Here, we focused on minimizing peptide loss during their transfer and storage in autosampler vials prior to analysis. Methods: We used commer...

This paper proposes a novel zone-based mobility management scheme, termed 1Zo (a single-zone scheme overlapped with the previous zone), to reduce signaling overhead caused by boundary ping-pong effects in wireless communication networks. The conventi...

Levoglucosenone-derived S- and N-adduct glycomimetics were evaluated as modulators of Pseudomonas aeruginosa PAO1 biofilms, with compounds 8, 9, and 11 selected for integrated analysis. At 100 µg/mL, they reduced biofilm biomass by 52–66%...

Type 2 diabetes (T2D) exhibits sex-dependent differences in islet β-cell dysfunction, yet the underlying molecular mechanisms remain unclear. By integrating two independent single-cell RNA sequencing datasets, we performed sex-stratified analyse...

Background: Leptospirosis notifications depend on infection, clinical expression and ascertainment, which may respond differently to rainfall and structural disadvantage. Objective: To examine the implications for surveillance in the Colombian Caribb...

To meet the engineering demand for seismic and subway-induced vibration dual control in transit-oriented development (TOD) over-track buildings, this paper proposes a metal rubber–polyurethane (MR-PU) composite bearing. Through multiple groups...

This paper presents a neural network-based approach designed to allow redundant robotic manipulators to replicate the arm motion of a human subject. The proposed approach uses a neural network trained on a custom-built motion tracking dataset to prop...

Rhaphiolepis salicifolia Lindley is a species of the family Rosaceae distributed in southern China. In this study, the chemical composition and biological properties of its essential oil (EO) were systematically investigated. A total of 79 constituen...

Understanding the factors that influence the sulfur compound circuit in clear-cell renal-cell carcinoma (ccRCC) is an important area of interest, particularly for studying pathomechanisms and developing personalized anticancer therapies. Sulfite oxid...

This study investigates hydrophobic natural deep eutectic solvents based on monoterpenoids and saturated fatty acids through a comprehensive experimental and molecular modeling approach. Eutectic mixtures, several of which had been previously reporte...

Despite 3D Concrete Printing (3DCP) being widely promoted as a solution to global housing deficits, feasibility studies rarely extend beyond high-income contexts. This perception study presents an exploratory analysis of perceived feasibility among 2...

Microviricetes are small circular single-stranded DNA bacteriophages found in diverse environments, but their diversity in masked palm civet fecal viromes remains poorly characterized. Here, viral metagenomic analysis of five pooled fecal libraries f...

Microwave breast imaging offers non-ionizing, non-invasive, and potentially more cost-effective tumor detection than traditional approaches. In this preliminary study, we investigate the location dependence of tumor-surrogate-induced reflection and c...

Porcine deltacoronavirus (PDCoV) is an emerging enteric coronavirus, and it has been isolated from clinical samples using multiple cells. Serial passaging in cell culture has been used to study viral adaptation and to generate attenuated vaccine cand...

Valorization of agro-industrial residues offers opportunities to develop active food packaging materials. This study investigated papaya leaf post-extraction residue (LW) and freeze-dried extract encapsulated in β-cyclodextrin (ELLE) as additive...

Petroleum-based plastics used in short-life packaging persist in the environment, which has driven the search for renewable and compostable alternatives. In this study, starch recovered from plantain (Musa paradisiaca, AAB group, AT1) and ‘Orin...

Background/Objectives: Surgical treatment for non-small cell lung cancer (NSCLC) presents risks of cancer-related cognitive impairment (CRCI) and postoperative cognitive dysfunction (POCD), which are further exacerbated by cancer-related fatigue. Whi...

Background: Among other immune escape mechanisms, unfavorable expression patterns of inhibitory checkpoint molecules (ICMs) and their ligands (ICMLs) in T cells and blasts are known to play a major role in the relapse of acute myeloid leukemia (AML)...

In the field of mechanical fault diagnosis, single-modal representations often fail to capture comprehensive fault characteristics of complex systems, leading to limited diagnostic accuracy and poor robustness against environmental interference. This...

The production and use of organic fertilizers and bioinputs can improve soil management and support more sustainable agricultural systems; however, evidence on their adoption following training programs among smallholder avocado farmers remains limit...

The crop planting structure is a key indicator for assessing agricultural sustainability. However, crop identification in complex plateau environments remains challenging due to limited spectral separability among crop types, low classification accur...