2,066,678 Results Found

Understanding complex interactions among social, economic, and environmental subsystems is essential for regional comprehensive sustainable development. Nevertheless, existing coupling-coordination studies lack sufficient targeted obstacle diagnosis...

Marine heatwaves (MHWs) are escalating threats to coral reef ecosystems, yet the host transcriptomic mechanisms underlying acclimatization to repeated thermal stress remain poorly understood. Using de novo RNA sequencing, we tracked the temporal tran...

Postoperative recurrence (POR) remains a common complication following ileocecal resection (ICR) in patients with Crohn’s disease (CD), and no therapy is currently approved. This study aimed to study the benefits of JAK/STAT pathway inhibition...

The construction sector contributes substantially to greenhouse gas emissions, largely because of Portland cement clinker production in cementitious composites. This study presents a cradle-to-gate life-cycle assessment of selected cementitious and a...

Highly lethal Vibrio disease (HLVD) is a newly emerging shrimp disease caused by VTc toxin-producing Vibrio strains, designated V_HLVD. VTc toxin, composed of VTcA, VTcB, and VTcC subunits, is a novel member of the Tc toxin family. Structural and func...

Optical metamaterials provide a versatile platform for manipulating the amplitude, phase, and polarization of light at subwavelength scales and are therefore attractive for compact polarization-control devices. However, simultaneously realizing broad...

Endosomal ClC-3 and ClC-4 Cl⁻/H⁺ antiporters are essential regulators of vesicular ion homeostasis and neuronal function, yet the mechanisms controlling their activity remain incompletely understood. TMEM9A has recently emerged as an accessory...

Advances in civil engineering and materials science have stimulated the development of innovative building materials capable of addressing the environmental, mechanical, and durability limitations of conventional construction materials [...]

Background/Objectives: Conventional interrupted microvascular anastomosis is technically demanding and time-consuming. We developed an intraluminal microtube anastomosis system (IMAS) in which circumferential anchoring ridges on the outer surface mec...

Background: Planarian neoblasts are pluripotent adult stem cells responsible for whole-body regeneration, yet antibody-based tools for their specific identification and isolation remain limited. This study aimed to generate a high-affinity single-cha...

Road freight transport is a cornerstone of the European Union’s logistics system, accounting for approximately three-quarters of inland freight activity while consuming a substantial share of transport energy. Despite extensive research on econ...

Hypervirulent Klebsiella pneumoniae (hvKP) causes invasive and metastatic infections and is increasingly acquiring carbapenem resistance. However, its laboratory identification remains challenging because hypermucoviscosity is an imperfect surrogate...

Urban greenways in dense cities face land constraints and changing ecological and social demands. This study develops a process-oriented framework from social–ecological systems (SES) theory and examines it through an explanatory documentary ca...

Chlorophyll-a (Chl-a) is an indicator of phytoplankton biomass but is not continuously measured at all water-quality monitoring sites. This study evaluated machine learning models for estimating Chl-a from routinely monitored water-quality variables,...

Objective: This study seeks to assess the prevalence of CD138-positive plasma cells in endometrial biopsies from women undergoing surgery for symptomatic caesarean scar defect (CSD) and examine associations with niche morphology, defect size, symptom...

Background/Objectives: Pancreatic ductal adenocarcinoma (PDAC) carries one of the worst prognoses among solid tumors, and biomarkers that complement standard pathological variables in patients undergoing resection followed by adjuvant chemotherapy ar...

Strongyle infections are common in horses and can cause clinically relevant disease, yet their associated inflammatory responses remain incompletely understood. Matrix metalloproteinase-9 (MMP-9), a key mediator of extracellular matrix degradation an...

Germline pathogenic variants in the aryl hydrocarbon receptor-interacting protein (AIP) gene are the most common identifiable genetic cause of familial isolated pituitary adenomas (FIPA) and are particularly associated with young-onset growth hormone...

Climate finance in Sub-Saharan Africa has grown, yet the region’s ecological footprint continues to exceed its biocapacity. Most studies treat climate finance as a single aggregate and estimate average effects. This study asks whether adaptatio...

Background/Objectives: Colorectal cancer and its chemotherapeutic treatment may be associated with gastrointestinal toxicity and nutritional deterioration. This study evaluated the association between exposure to 5-fluorouracil (5-FU) or capecitabine...

Background/Objectives: Melanoma-associated antigen A3 (MAGEA3) is a cancer–testis antigen with potential biological and prognostic relevance in pancreatic ductal adenocarcinoma (PDAC). This study evaluated the association between OTI1H1-defined...

High-quality images are essential for several computer-vision applications. Hence, low-contrast images often pose significant challenges because they can cause failures in automated detection and analysis processes. This study presents an innovative...

MicroRNA-2c (miR-2c) has previously been implicated in shell formation in the pearl oyster Pinctada fucata martensii, but its broader downstream regulatory network remains unclear. Here, mantle tissues following in vivo miR-2c overexpression (M2, n =...

Purpose: Maxillofacial metastases from prostate cancer account for 9–11% of metastatic jaw lesions. The optimal imaging technique for suspected maxillofacial metastases remains undefined. Conventional imaging often lacks sensitivity for early d...

Harvesting operations are time-sensitive and vulnerable to weather-related disruptions, making effective field dispatching important for minimizing crop loss. This study extends a previously developed multi-agent discrete-event simulation of Japanese...

To compare the effects of different diets on the life-history traits and stage-specific UV-B tolerance of the brine shrimp Artemia franciscana, individuals were fed with H. pluvialis powder (20 mg/L), baker’s yeast powder (10 mg/L), or Dunaliel...

In recent years, natural dental care products have gained popularity due to their antiseptic, antibacterial, antifungal, antioxidant, antiviral, and analgesic properties. In this study the efficacy of herbal-based mouthwash and spray (GlimoTM, Haltro...

Ground fault detection in DC-links of high-voltage AC drives is challenging because faults may not produce large currents, while neutral-point voltage monitoring can lose sensitivity under nearly balanced pole-to-ground conductances. This paper devel...

Comparison of the newly determined structures of Forms II and III with the previously reported Form I reveals closely similar, essentially planar molecular conformations across the three crystal forms. Hirshfeld surface analysis showed broadly relate...

Background/Objectives: Gastrointestinal stromal tumors (GISTs) are primarily identified using KIT and DOG1 immunohistochemistry, although staining may be absent or heterogeneous in some cases. Cytoplasmic Wilms tumor 1 (WT1) expression has been repor...

The study examines the use of stone sludge generated during the processing of natural stone. The aim is to verify its benefits in the production of concrete at stonemasonry workshops, particularly with regard to reducing the volume of by-products pro...

Background: Patient-specific seizure prediction remains challenging because preictal EEG patterns and channel relevance vary substantially across individuals. Methods: We propose a CNN-GCN-Diffusion Network (CGD-Net) integrating channel-wise temporal...

Extreme floods and storms can disrupt essential services not just through direct physical damage but also through cascading effects across interconnected critical infrastructure. This study provides multi-event empirical evidence of how flood- and st...

In residential photovoltaic (PV) energy storage systems, the bidirectional DC–DC converter between the DC bus and the battery must operate efficiently over wide input- and output-voltage ranges. This paper presents the design and implementation...

Background/Objectives: Artificial intelligence (AI) may standardise radiographic measurement of component position, but its accuracy is uncertain. We assessed agreement between AI and reference-standard measurements after primary total hip (THA) and...

This paper systematically studies a space-fractional variable-coefficient Toda (sfvToda) lattice equation. The core innovation of this paper lies in incorporating both fractional power of the recursion operator and time-varying coefficients into the...

Rapid technological iteration has turned electric vehicle (EV) purchasing into a decision about timing: buy now, or wait for a better model. Prior research explains how favorably consumers evaluate EVs, but not when they intend to buy. It also treats...

Surrogate models can reproduce wastewater effluent trajectories accurately, but their use in optimization also requires a suitable representation of the response to control actions. This paper proposes an actionability-aware framework for assessing a...

Although vital to urban operations, urban freight transport (UFT) generates substantial negative externalities. Despite the rising interest in urban transport sustainability, methodological frameworks targeting UFT remain scarce, particularly those t...

Abandoned and underused sites offer opportunities to reconnect contemporary public landscapes with spatial traces and cultural narratives. This study examines how adaptive reuse (AR) and conceptual landscape design (CLD) represent intended place iden...

Glyphosate-resistant annual ryegrass (Lolium rigidum) is a major problem in Australian grain production. Early detection of resistant populations is important for effective management, yet current bioassay-based detection takes 21–28 days. Here...

Conventional gamma-ray logging estimates uranium indirectly from daughter-product activity and can therefore produce substantial bias in formations affected by uranium–radium disequilibrium. This study develops and field-validates an integrated...

Ceftriaxone and ciprofloxacin are WHO Highest Priority Critically Important Antimicrobials (HPCIAs) for the treatment of severe and invasive infections caused by non-typhoidal Salmonella (NTS). This study aimed to develop linear regression models bas...

Robotic-assisted surgery (RAS) has transformed minimally invasive procedures by improving physical ergonomics, surgical field visualisation and instrument manipulation. However, RAS introduces unique cognitive load for the surgeon. Cognitive ergonomi...

Policy-led housing renewal and standardized rural-house atlases are reshaping contemporary Yi rural housing, yet trade-offs among energy performance, winter cold discomfort, and daylighting remain poorly quantified. This study aimed to quantify the e...

Background and Objectives: This study aimed to compare the associations of total weekly physical activity (PA) volume and time spent/day in moderate-to-vigorous PA (MVPA) with physical-functional outcomes in individuals with COPD. Methods: Patients u...

Bacteriophage vB_SalS_KY05 (KY05) was propagated using a non-pathogenic E. coli K-12 strain. The lysate was administered via water for 56 days. Thirty Lohmann Brown-Classic laying hens (53 weeks old) were randomly assigned to three groups: the Contro...

Background/Objectives: Procalcitonin has been proposed as an alternative or complementary biomarker to calcitonin in medullary thyroid carcinoma (MTC). We synthesised the published systematic reviews, appraised their quality, and measured their relia...

Bone tissue regeneration remains a major clinical challenge, and exosomes secreted by mesenchymal stem cells (MSCs) have emerged as attractive cell-free therapeutic tools. To enhance their efficacy and local action, exosomes can be modified to enrich...

The adoption of virtual reality (VR) in higher education depends partly on how usable and acceptable VR resources are perceived to be. This two-phase study evaluated a 360° VR learning object about women scientists commemorated in the street name...