Special Issue "Hantaviruses"
Deadline for manuscript submissions: closed (30 November 2013)
Dr. Heinz Feldmann
Chief, Laboratory of Virology, NIAID, Building 28, Room 2A100A 903 4th Street Hamilton, MT 59840, USA
Dr. David Safronetz
Laboratory of Virology, NIAID, Building 28, Room 2A100A 903 4th Street Hamilton, MT 59840, USA
The genus hantavirus is comprised of a unique group of viruses within the Bunyaviridae which are maintained in nature and transmitted to humans via small vertebrates, predominantly rodents. In humans hantaviruses, including Hantaan, Dobrava, Puumala, Sin Nombre and Andes viruses, are responsible for two diseases; hemorrhagic fever with renal syndrome (HFRS) and the more recently recognized hantavirus pulmonary syndrome (HPS). Combined hantaviruses have a world-wide distribution with HFRS primarily occurring in Europe and Asia with an incidence of greater than 100,000 cases annually and mortality rates of up to 15%, and HPS documented throughout the America’s with mortality rates often exceeding 30%. Despite the significant morbidity and mortality associated with this group of pathogens vaccines, antivirals and therapeutics are largely non-existent. The past several years has seen renewed research interest on several aspects of hantaviruses. The present Special Issue covers recent developments in hantavirus biology, including ecology, clinical presentation and diagnostic approaches, molecular pathogenesis, mechanisms of virus-host cell interaction, disease modeling and the development of novel therapeutic strategies against these important pathogens.
Dr. Heinz Feldmann
Dr. David Safronetz
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed Open Access monthly journal published by MDPI.
- emerging viruses
- hantavirus pulmonary syndrome
- hemorrhagic fever with renal syndrome
Article: Development of a One-Step SYBR Green I Real-Time RT-PCR Assay for the Detection and Quantitation of Araraquara and Rio Mamore Hantavirus
Viruses 2013, 5(9), 2272-2281; doi:10.3390/v5092272
Received: 13 July 2013; in revised form: 10 September 2013 / Accepted: 17 September 2013 / Published: 19 September 2013| Download PDF Full-text (4985 KB) | Download XML Full-text
Short Communication: Increased Detection of Sin Nombre Hantavirus RNA in Antibody-Positive Deer Mice from Montana, USA: Evidence of Male Bias in RNA Viremia
Viruses 2013, 5(9), 2320-2328; doi:10.3390/v5092320
Received: 30 July 2013; in revised form: 13 September 2013 / Accepted: 19 September 2013 / Published: 24 September 2013| Download PDF Full-text (73 KB) | Download XML Full-text
Article: Ribavirin Protects Syrian Hamsters against Lethal Hantavirus Pulmonary Syndrome — After Intranasal Exposure to Andes Virus
Viruses 2013, 5(11), 2704-2720; doi:10.3390/v5112704
Received: 5 September 2013; in revised form: 23 October 2013 / Accepted: 31 October 2013 / Published: 8 November 2013| Download PDF Full-text (871 KB) | Download XML Full-text
Last update: 25 November 2013