Viruses 2014, 6(2), 524-534; doi:10.3390/v6020524
Article

Prevalence of Antibodies against Hantaviruses in Serum and Saliva of Adults Living or Working on Farms in Yorkshire, United Kingdom

1 Microbiology Services, Public Health England, Porton Down, Wiltshire, SP4 0JG, UK 2 Institute of Infection and Global Health, University of Liverpool, Liverpool, L69 7BE, UK 3 Public Health England, Yorkshire and the Humber, York, YO41 1LZ, UK 4 Field Epidemiology Services, Public Health England, Leeds, LS2 7UE, UK 5 Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK
* Author to whom correspondence should be addressed.
Received: 2 December 2013; in revised form: 23 January 2014 / Accepted: 25 January 2014 / Published: 5 February 2014
(This article belongs to the Special Issue Hantaviruses)
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Abstract: Hantaviruses are an established cause of haemorrhagic fever with renal syndrome (HFRS) in Europe. Following a confirmed case of HFRS in the UK, in an individual residing on a farm in North Yorkshire and the Humber, a tidal estuary on the east coast of Northern England, and the subsequent isolation of a Seoul hantavirus from rats trapped on the patient’s farm, it was considered appropriate to further investigate the public health risk of this virus in the region. Of a total 119 individuals tested, nine (7.6%) were seropositive for hantavirus antibodies. Seven of the seropositive samples showed a stronger reaction to Seoul and Hantaan compared to other clinically relevant hantaviruses. Observation of rodents during the day, in particular mice, was associated with a reduced risk of seropositivity. In addition to one region known to be at risk following an acute case, five further potential risk areas have been identified. This study supports recently published evidence that hantaviruses are likely to be of public health interest in the region.
Keywords: farmers; hantavirus; serology; saliva; serosurveillance; haemorrhagic fever with renal syndrome; Seoul virus

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MDPI and ACS Style

Jameson, L.J.; Newton, A.; Coole, L.; Newman, E.N.C.; Carroll, M.W.; Beeching, N.J.; Hewson, R.; Christley, R.M. Prevalence of Antibodies against Hantaviruses in Serum and Saliva of Adults Living or Working on Farms in Yorkshire, United Kingdom. Viruses 2014, 6, 524-534.

AMA Style

Jameson LJ, Newton A, Coole L, Newman ENC, Carroll MW, Beeching NJ, Hewson R, Christley RM. Prevalence of Antibodies against Hantaviruses in Serum and Saliva of Adults Living or Working on Farms in Yorkshire, United Kingdom. Viruses. 2014; 6(2):524-534.

Chicago/Turabian Style

Jameson, Lisa J.; Newton, Autilia; Coole, Louise; Newman, Edmund N.C.; Carroll, Miles W.; Beeching, Nick J.; Hewson, Roger; Christley, Robert M. 2014. "Prevalence of Antibodies against Hantaviruses in Serum and Saliva of Adults Living or Working on Farms in Yorkshire, United Kingdom." Viruses 6, no. 2: 524-534.

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