Special Issue "Non-Coding RNAs 2012"

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A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry, Molecular Biology and Biophysics".

Deadline for manuscript submissions: closed (31 October 2012)

Special Issue Editor

Guest Editor
Prof. Dr. Constantinos Stathopoulos
Department of Biochemistry, School of Medicine, University of Patras, 1 Asklipiou st., 26504 Patras, Greece
Website: http://biochemistry.med.upatras.gr/lang_en/laboratory/viewCV/2
E-Mail: cstath@med.upatras.gr
Phone: +30 2610 997932 (office); +30 2610 997936 (lab)
Fax: +30 2610 969167

Special Issue Information

Dear Colleagues,

During recent years, a remarkable expansion of the “RNA world” members has been observed with the discovery and characterization of many elusive, so far, RNA molecules of various sizes and regulatory roles, in both eukaryotes and bacteria. In the dawn of this new RNA era, the term “non-coding RNAs” represents not only molecules such as tRNAs, rRNAs and snoRNAs, that cannot be translated into proteins. Instead, it additionally includes a variety of prominent RNA molecules that play distinct and critical roles within the cell. In eukaryotes, these novel members are represented by numerous microRNAs, siRNAs, piRNAs and long non-coding RNAs, that exhibit trans-acting antisense modulating properties. Today, we know that they modulate gene expression by interfering in post-transcriptional level. Moreover, RNA interference-based methodologies have provided the means of studying gene expression at a glance, both in vitro and in vivo, and they have emerged as very delicate and promising therapeutic strategies. In bacteria, the new members are represented by many regulatory RNAs of various sizes, which are also responsible for essential cellular responses. These key elements, can either be embedded in the 5’ end of mRNAs (i.e. riboswitches), they can be small RNAs that act in trans by targeting proteins or RNAs, they can be long antisense RNA modulators (CRISPR RNAs) or they may even have intrinsic activity (like RNase P ribozyme). Whatever their origin, size, structure or specific role, it is more than evident that non-coding RNAs represent a dynamic and expanding family of essential molecules, some of them with deep evolutionary history. Moreover, they are established as valuable novel tools with biotechnological applications or/and targets for combating disease or pathogens. Their discovery and study has great impact not only in the way we approach specific cellular processes today, but also in the way we understand the evolution of life itself.

Prof. Dr. Constantinos Stathopoulos
Guest Editor

Similar Special Issues could be found in the following:
Special Issue "Regulation by non-coding RNAs" http://www.mdpi.com/journal/ijms/special_issues/regulation-by-non-coding-rnas
Special Issue "Non-Coding RNAs" http://www.mdpi.com/journal/ijms/special_issues/noncoding_RNAs

Keywords

  • tRNA
  • rRNA
  • snoRNA
  • ribozyme
  • microRNA
  • siRNA
  • piRNA
  • riboswitch
  • sRNA
  • CRISPR RNA

Published Papers (21 papers)

by ,  and
Int. J. Mol. Sci. 2013, 14(3), 6144-6156; doi:10.3390/ijms14036144
Received: 20 November 2012; in revised form: 28 January 2013 / Accepted: 28 February 2013 / Published: 18 March 2013
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by , ,  and
Int. J. Mol. Sci. 2013, 14(3), 5519-5544; doi:10.3390/ijms14035519
Received: 21 January 2013; in revised form: 26 February 2013 / Accepted: 4 March 2013 / Published: 8 March 2013
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by  and
Int. J. Mol. Sci. 2013, 14(3), 4560-4579; doi:10.3390/ijms14034560
Received: 18 January 2013; in revised form: 10 February 2013 / Accepted: 16 February 2013 / Published: 26 February 2013
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by , , , , , , ,  and
Int. J. Mol. Sci. 2013, 14(2), 4298-4316; doi:10.3390/ijms14024298
Received: 3 December 2012; in revised form: 29 January 2013 / Accepted: 6 February 2013 / Published: 21 February 2013
Show/Hide Abstract | Cited by 4 | PDF Full-text (601 KB) | HTML Full-text | XML Full-text

by , , , , , ,  and
Int. J. Mol. Sci. 2013, 14(2), 2717-2738; doi:10.3390/ijms14022717
Received: 10 November 2012; in revised form: 9 January 2013 / Accepted: 15 January 2013 / Published: 28 January 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (759 KB) | HTML Full-text | XML Full-text | Supplementary Files

by , , , , ,  and
Int. J. Mol. Sci. 2013, 14(1), 2072-2084; doi:10.3390/ijms14012072
Received: 6 November 2012; in revised form: 11 December 2012 / Accepted: 17 January 2013 / Published: 22 January 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (492 KB) | HTML Full-text | XML Full-text | Supplementary Files

by ,  and
Int. J. Mol. Sci. 2013, 14(1), 1822-1842; doi:10.3390/ijms14011822
Received: 20 November 2012; in revised form: 28 December 2012 / Accepted: 10 January 2013 / Published: 16 January 2013
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by  and
Int. J. Mol. Sci. 2013, 14(1), 1566-1588; doi:10.3390/ijms14011566
Received: 12 December 2012; in revised form: 31 December 2012 / Accepted: 4 January 2013 / Published: 14 January 2013
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by ,  and
Int. J. Mol. Sci. 2013, 14(1), 1516-1540; doi:10.3390/ijms14011516
Received: 21 November 2012; in revised form: 9 December 2012 / Accepted: 10 December 2012 / Published: 14 January 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (956 KB) | HTML Full-text | XML Full-text

by , , , , , , ,  and
Int. J. Mol. Sci. 2013, 14(1), 1105-1118; doi:10.3390/ijms14011105
Received: 31 October 2012; in revised form: 11 December 2012 / Accepted: 24 December 2012 / Published: 8 January 2013
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by , , ,  and
Int. J. Mol. Sci. 2013, 14(1), 611-624; doi:10.3390/ijms14010611
Received: 2 November 2012; in revised form: 14 December 2012 / Accepted: 18 December 2012 / Published: 28 December 2012
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by  and
Int. J. Mol. Sci. 2013, 14(1), 480-495; doi:10.3390/ijms14010480
Received: 12 November 2012; in revised form: 6 December 2012 / Accepted: 6 December 2012 / Published: 27 December 2012
Show/Hide Abstract | Cited by 5 | PDF Full-text (363 KB) | HTML Full-text | XML Full-text

by , , ,  and
Int. J. Mol. Sci. 2013, 14(1), 378-393; doi:10.3390/ijms14010378
Received: 5 November 2012; in revised form: 11 December 2012 / Accepted: 14 December 2012 / Published: 24 December 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (268 KB) | HTML Full-text | XML Full-textCorrection | Supplementary Files

by , , , , , , ,  and
Int. J. Mol. Sci. 2013, 14(1), 205-225; doi:10.3390/ijms14010205
Received: 5 November 2012; in revised form: 30 November 2012 / Accepted: 10 December 2012 / Published: 21 December 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (6531 KB) | HTML Full-text | XML Full-text | Supplementary Files

by  and
Int. J. Mol. Sci. 2012, 13(12), 16708-16717; doi:10.3390/ijms131216708
Received: 5 November 2012; in revised form: 3 December 2012 / Accepted: 3 December 2012 / Published: 6 December 2012
Show/Hide Abstract | Cited by 3 | PDF Full-text (299 KB) | HTML Full-text | XML Full-text

by , , , ,  and
Int. J. Mol. Sci. 2012, 13(12), 16554-16579; doi:10.3390/ijms131216554
Received: 29 October 2012; in revised form: 21 November 2012 / Accepted: 21 November 2012 / Published: 5 December 2012
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by ,  and
Int. J. Mol. Sci. 2012, 13(12), 16223-16240; doi:10.3390/ijms131216223
Received: 21 October 2012; in revised form: 21 November 2012 / Accepted: 27 November 2012 / Published: 30 November 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (1828 KB) | HTML Full-text | XML Full-text | Supplementary Files

by , ,  and
Int. J. Mol. Sci. 2012, 13(12), 15826-15847; doi:10.3390/ijms131215826
Received: 1 November 2012; in revised form: 20 November 2012 / Accepted: 21 November 2012 / Published: 27 November 2012
Show/Hide Abstract | Cited by 7 | PDF Full-text (358 KB) | HTML Full-text | XML Full-text

by , ,  and
Int. J. Mol. Sci. 2012, 13(12), 15496-15509; doi:10.3390/ijms131215496
Received: 29 October 2012; in revised form: 16 November 2012 / Accepted: 19 November 2012 / Published: 22 November 2012
Show/Hide Abstract | Cited by 2 | PDF Full-text (4197 KB) | HTML Full-text | XML Full-text

by ,  and
Int. J. Mol. Sci. 2012, 13(10), 13134-13139; doi:10.3390/ijms131013134
Received: 31 July 2012; in revised form: 22 September 2012 / Accepted: 26 September 2012 / Published: 12 October 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (363 KB) | HTML Full-text | XML Full-text

by  and
Int. J. Mol. Sci. 2012, 13(7), 8449-8466; doi:10.3390/ijms13078449
Received: 8 June 2012; in revised form: 29 June 2012 / Accepted: 2 July 2012 / Published: 9 July 2012
Show/Hide Abstract | Cited by 3 | PDF Full-text (427 KB) | HTML Full-text | XML Full-text

Last update: 26 February 2014

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