Special Issue "Autophagy"

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A special issue of Cells (ISSN 2073-4409).

Deadline for manuscript submissions: 20 March 2015

Special Issue Editors

Guest Editor
Dr. Anne Hamacher-Brady
Lysosomal Systems Biology, German Cancer Research Center (DKFZ) and BioQuant, INF 267, 69120 Heidelberg, Germany
Website: http://bradylabs.bioquant.uni-heidelberg.de
E-Mail: a.hamacher@dkfz.de
Phone: +49 6221 5451322
Interests: autophagy; programmed cell death; apoptosis; lysosomes; cell biology; cancer research; cardiovascular disease

Guest Editor
Dr. Nathan R. Brady
Research Group of Systems Biology of Cell Death Mechanisms, German Cancer Research Center (DKFZ), and Department of Surgery, Medical Faculty, University of Heidelberg, BioQuant, INF 267, 69120 Heidelberg, Germany
Website: http://bradylabs.bioquant.uni-heidelberg.de
E-Mail: n.brady@dkfz.de
Phone: +49 6221 5451 357
Interests: autophagy; autophagy receptors; BH3-only proteins; apoptosis; quantitative microscopy; systems biology; dynamic modeling of signal transduction; data-driven modeling

Special Issue Information

Dear Colleagues,

Since the description of its molecular machinery began in the late 1990s, our understanding of autophagy, the process of intracellular (self-)digestion via lysosomes, has made an exceptional progress. Today, autophagy is recognized as an integral component of cellular physiology and pathophysiology. Autophagy has evolved from being regarded as a mechanism for the degradation of random cellular components to a heterogeneous and highly regulated process, capable of specificity. Through the degradation of a large variety of substrates, including proteins, protein aggregates, organelles, and intracellular pathogens, autophagy influences virtually all vital cellular functions and signaling pathways. Consequently, autophagy is intimately connected with cellular homeostasis and development and progression of diseases such as cancer, neurodegeneration, infection, and autoimmune disorders.

This Special Issue offers an Open Access forum that aims at bringing together a collection of original research and review articles addressing the expanding field of autophagy. To that end we are welcoming contributions which may cover molecular machinery, substrate specificity, regulation of autophagy and its crosstalk with essential cell signaling programs, in the context of the cell’s homeostatic and stress signaling.  We hope to provide a stimulating resource for the fascinating subject of autophagy.

Dr. Anne Hamacher-Brady
Dr. Nathan R. Brady
Guest Editors

Keywords

  • autophagy
  • autophagosomes
  • lysosomes
  • degradation
  • ubiquitin
  • p62
  • mitophagy
  • programmed cell death
  • reactive oxygen species
  • metabolism

Published Papers (20 papers)

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p. 83-104
by ,  and
Cells 2013, 2(1), 83-104; doi:10.3390/cells2010083
Received: 17 September 2012; in revised form: 31 October 2012 / Accepted: 7 November 2012 / Published: 25 January 2013
Show/Hide Abstract | Cited by 5 | PDF Full-text (878 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Autophagy)
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p. 754-773
by
Cells 2012, 1(4), 754-773; doi:10.3390/cells1040754
Received: 30 June 2012; in revised form: 3 August 2012 / Accepted: 18 September 2012 / Published: 15 October 2012
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(This article belongs to the Special Issue Autophagy)
p. 597-616
by  and
Cells 2012, 1(3), 597-616; doi:10.3390/cells1030597
Received: 19 July 2012; in revised form: 10 August 2012 / Accepted: 14 August 2012 / Published: 27 August 2012
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(This article belongs to the Special Issue Autophagy)
p. 617-630
by  and
Cells 2012, 1(3), 617-630; doi:10.3390/cells1030617
Received: 1 July 2012; in revised form: 11 August 2012 / Accepted: 21 August 2012 / Published: 27 August 2012
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(This article belongs to the Special Issue Autophagy)
p. 558-575
by , ,  and
Cells 2012, 1(3), 558-575; doi:10.3390/cells1030558
Received: 17 June 2012; in revised form: 11 August 2012 / Accepted: 16 August 2012 / Published: 23 August 2012
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(This article belongs to the Special Issue Autophagy)
p. 535-557
by , ,  and
Cells 2012, 1(3), 535-557; doi:10.3390/cells1030535
Received: 7 May 2012; in revised form: 4 July 2012 / Accepted: 1 August 2012 / Published: 21 August 2012
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(This article belongs to the Special Issue Autophagy)
p. 520-534
by , ,  and
Cells 2012, 1(3), 520-534; doi:10.3390/cells1030520
Received: 14 June 2012; in revised form: 28 June 2012 / Accepted: 30 July 2012 / Published: 13 August 2012
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(This article belongs to the Special Issue Autophagy)
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p. 464-491
by ,  and
Cells 2012, 1(3), 464-491; doi:10.3390/cells1030464
Received: 15 June 2012; in revised form: 9 July 2012 / Accepted: 19 July 2012 / Published: 3 August 2012
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(This article belongs to the Special Issue Autophagy)
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p. 492-519
by  and
Cells 2012, 1(3), 492-519; doi:10.3390/cells1030492
Received: 18 June 2012; in revised form: 20 July 2012 / Accepted: 23 July 2012 / Published: 3 August 2012
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(This article belongs to the Special Issue Autophagy)
p. 449-463
by ,  and
Cells 2012, 1(3), 449-463; doi:10.3390/cells1030449
Received: 2 May 2012; in revised form: 7 June 2012 / Accepted: 17 July 2012 / Published: 2 August 2012
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(This article belongs to the Special Issue Autophagy)
p. 428-448
by , ,  and
Cells 2012, 1(3), 428-448; doi:10.3390/cells1030428
Received: 9 May 2012; in revised form: 28 June 2012 / Accepted: 18 July 2012 / Published: 2 August 2012
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(This article belongs to the Special Issue Autophagy)
p. 396-408
by  and
Cells 2012, 1(3), 396-408; doi:10.3390/cells1030396
Received: 13 June 2012; in revised form: 21 July 2012 / Accepted: 23 July 2012 / Published: 30 July 2012
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(This article belongs to the Special Issue Autophagy)
p. 346-371
by ,  and
Cells 2012, 1(3), 346-371; doi:10.3390/cells1030346
Received: 28 June 2012; in revised form: 14 July 2012 / Accepted: 16 July 2012 / Published: 27 July 2012
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(This article belongs to the Special Issue Autophagy)
p. 372-395
by ,  and
Cells 2012, 1(3), 372-395; doi:10.3390/cells1030372
Received: 7 May 2012; in revised form: 22 June 2012 / Accepted: 13 July 2012 / Published: 27 July 2012
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(This article belongs to the Special Issue Autophagy)
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p. 325-345
by  and
Cells 2012, 1(3), 325-345; doi:10.3390/cells1030325
Received: 4 May 2012; in revised form: 18 June 2012 / Accepted: 13 July 2012 / Published: 26 July 2012
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(This article belongs to the Special Issue Autophagy)
p. 284-312
by ,  and
Cells 2012, 1(3), 284-312; doi:10.3390/cells1030284
Received: 14 May 2012; in revised form: 6 June 2012 / Accepted: 15 June 2012 / Published: 6 July 2012
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(This article belongs to the Special Issue Autophagy)
p. 263-283
by  and
Cells 2012, 1(3), 263-283; doi:10.3390/cells1030263
Received: 9 May 2012; in revised form: 14 June 2012 / Accepted: 19 June 2012 / Published: 4 July 2012
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(This article belongs to the Special Issue Autophagy)
p. 248-262
by
Cells 2012, 1(3), 248-262; doi:10.3390/cells1030248
Received: 23 May 2012; in revised form: 19 June 2012 / Accepted: 20 June 2012 / Published: 29 June 2012
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(This article belongs to the Special Issue Autophagy)
p. 204-247
by  and
Cells 2012, 1(3), 204-247; doi:10.3390/cells1030204
Received: 16 May 2012; in revised form: 13 June 2012 / Accepted: 14 June 2012 / Published: 25 June 2012
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(This article belongs to the Special Issue Autophagy)
p. 168-203
by , , , ,  and
Cells 2012, 1(2), 168-203; doi:10.3390/cells1020168
Received: 10 May 2012; in revised form: 3 June 2012 / Accepted: 12 June 2012 / Published: 20 June 2012
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(This article belongs to the Special Issue Autophagy)
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Last update: 4 November 2014

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