Special Issue "Autophagy"

Quicklinks

A special issue of Cells (ISSN 2073-4409).

Deadline for manuscript submissions: 15 November 2014

Special Issue Editors

Guest Editor
Dr. Anne Hamacher-Brady
Lysosomal Systems Biology, German Cancer Research Center (DKFZ) and BioQuant, INF 267, 69120 Heidelberg, Germany
Website: http://bradylabs.bioquant.uni-heidelberg.de
E-Mail: a.hamacher@dkfz.de
Phone: +49 6221 5451322
Interests: autophagy; programmed cell death; apoptosis; lysosomes; cell biology; cancer research; cardiovascular disease

Guest Editor
Dr. Nathan R. Brady
Research Group of Systems Biology of Cell Death Mechanisms, German Cancer Research Center (DKFZ), and Department of Surgery, Medical Faculty, University of Heidelberg, BioQuant, INF 267, 69120 Heidelberg, Germany
Website: http://bradylabs.bioquant.uni-heidelberg.de
E-Mail: n.brady@dkfz.de
Phone: +49 6221 5451 357
Interests: autophagy; autophagy receptors; BH3-only proteins; apoptosis; quantitative microscopy; systems biology; dynamic modeling of signal transduction; data-driven modeling

Special Issue Information

Dear Colleagues,

Since the description of its molecular machinery began in the late 1990s, our understanding of autophagy, the process of intracellular (self-)digestion via lysosomes, has made an exceptional progress. Today, autophagy is recognized as an integral component of cellular physiology and pathophysiology. Autophagy has evolved from being regarded as a mechanism for the degradation of random cellular components to a heterogeneous and highly regulated process, capable of specificity. Through the degradation of a large variety of substrates, including proteins, protein aggregates, organelles, and intracellular pathogens, autophagy influences virtually all vital cellular functions and signaling pathways. Consequently, autophagy is intimately connected with cellular homeostasis and development and progression of diseases such as cancer, neurodegeneration, infection, and autoimmune disorders.

This Special Issue offers an Open Access forum that aims at bringing together a collection of original research and review articles addressing the expanding field of autophagy. To that end we are welcoming contributions which may cover molecular machinery, substrate specificity, regulation of autophagy and its crosstalk with essential cell signaling programs, in the context of the cell’s homeostatic and stress signaling.  We hope to provide a stimulating resource for the fascinating subject of autophagy.

Dr. Anne Hamacher-Brady
Dr. Nathan R. Brady
Guest Editor

Keywords

  • autophagy
  • autophagosomes
  • lysosomes
  • degradation
  • ubiquitin
  • p62
  • mitophagy
  • programmed cell death
  • reactive oxygen species
  • metabolism

Published Papers (20 papers)

Cells 2013, 2(1), 83-104; doi:10.3390/cells2010083
Received: 17 September 2012; in revised form: 31 October 2012 / Accepted: 7 November 2012 / Published: 25 January 2013
Show/Hide Abstract | Download PDF Full-text (878 KB) | View HTML Full-text | Download XML Full-text
abstract graphic

Cells 2012, 1(4), 754-773; doi:10.3390/cells1040754
Received: 30 June 2012; in revised form: 3 August 2012 / Accepted: 18 September 2012 / Published: 15 October 2012
Show/Hide Abstract | Download PDF Full-text (221 KB) | View HTML Full-text | Download XML Full-text

Cells 2012, 1(3), 617-630; doi:10.3390/cells1030617
Received: 1 July 2012; in revised form: 11 August 2012 / Accepted: 21 August 2012 / Published: 27 August 2012
Show/Hide Abstract | Download PDF Full-text (299 KB) | View HTML Full-text | Download XML Full-text

Cells 2012, 1(3), 597-616; doi:10.3390/cells1030597
Received: 19 July 2012; in revised form: 10 August 2012 / Accepted: 14 August 2012 / Published: 27 August 2012
Show/Hide Abstract | Download PDF Full-text (456 KB) | View HTML Full-text | Download XML Full-text

Cells 2012, 1(3), 558-575; doi:10.3390/cells1030558
Received: 17 June 2012; in revised form: 11 August 2012 / Accepted: 16 August 2012 / Published: 23 August 2012
Show/Hide Abstract | Download PDF Full-text (697 KB) | View HTML Full-text | Download XML Full-text

Cells 2012, 1(3), 535-557; doi:10.3390/cells1030535
Received: 7 May 2012; in revised form: 4 July 2012 / Accepted: 1 August 2012 / Published: 21 August 2012
Show/Hide Abstract | Download PDF Full-text (435 KB) | View HTML Full-text | Download XML Full-text

Cells 2012, 1(3), 520-534; doi:10.3390/cells1030520
Received: 14 June 2012; in revised form: 28 June 2012 / Accepted: 30 July 2012 / Published: 13 August 2012
Show/Hide Abstract | Download PDF Full-text (1173 KB) | View HTML Full-text | Download XML Full-text |  Supplementary Files
abstract graphic

Cells 2012, 1(3), 492-519; doi:10.3390/cells1030492
Received: 18 June 2012; in revised form: 20 July 2012 / Accepted: 23 July 2012 / Published: 3 August 2012
Show/Hide Abstract | Download PDF Full-text (669 KB) | View HTML Full-text | Download XML Full-text

Cells 2012, 1(3), 464-491; doi:10.3390/cells1030464
Received: 15 June 2012; in revised form: 9 July 2012 / Accepted: 19 July 2012 / Published: 3 August 2012
Show/Hide Abstract | Download PDF Full-text (582 KB) | View HTML Full-text | Download XML Full-text
abstract graphic

Cells 2012, 1(3), 449-463; doi:10.3390/cells1030449
Received: 2 May 2012; in revised form: 7 June 2012 / Accepted: 17 July 2012 / Published: 2 August 2012
Show/Hide Abstract | Download PDF Full-text (268 KB) | View HTML Full-text | Download XML Full-text

Cells 2012, 1(3), 428-448; doi:10.3390/cells1030428
Received: 9 May 2012; in revised form: 28 June 2012 / Accepted: 18 July 2012 / Published: 2 August 2012
Show/Hide Abstract | Download PDF Full-text (1037 KB) | View HTML Full-text | Download XML Full-text

Cells 2012, 1(3), 396-408; doi:10.3390/cells1030396
Received: 13 June 2012; in revised form: 21 July 2012 / Accepted: 23 July 2012 / Published: 30 July 2012
Show/Hide Abstract | Download PDF Full-text (600 KB) | View HTML Full-text | Download XML Full-text

Cells 2012, 1(3), 372-395; doi:10.3390/cells1030372
Received: 7 May 2012; in revised form: 22 June 2012 / Accepted: 13 July 2012 / Published: 27 July 2012
Show/Hide Abstract | Download PDF Full-text (409 KB) | View HTML Full-text | Download XML Full-text
abstract graphic

Cells 2012, 1(3), 346-371; doi:10.3390/cells1030346
Received: 28 June 2012; in revised form: 14 July 2012 / Accepted: 16 July 2012 / Published: 27 July 2012
Show/Hide Abstract | Download PDF Full-text (1706 KB) | View HTML Full-text | Download XML Full-text

Cells 2012, 1(3), 325-345; doi:10.3390/cells1030325
Received: 4 May 2012; in revised form: 18 June 2012 / Accepted: 13 July 2012 / Published: 26 July 2012
Show/Hide Abstract | Download PDF Full-text (352 KB) | View HTML Full-text | Download XML Full-text

Cells 2012, 1(3), 284-312; doi:10.3390/cells1030284
Received: 14 May 2012; in revised form: 6 June 2012 / Accepted: 15 June 2012 / Published: 6 July 2012
Show/Hide Abstract | Download PDF Full-text (405 KB) | Download XML Full-text

Cells 2012, 1(3), 263-283; doi:10.3390/cells1030263
Received: 9 May 2012; in revised form: 14 June 2012 / Accepted: 19 June 2012 / Published: 4 July 2012
Show/Hide Abstract | Download PDF Full-text (235 KB) | Download XML Full-text

Cells 2012, 1(3), 248-262; doi:10.3390/cells1030248
Received: 23 May 2012; in revised form: 19 June 2012 / Accepted: 20 June 2012 / Published: 29 June 2012
Show/Hide Abstract | Download PDF Full-text (93 KB) | Download XML Full-text

Cells 2012, 1(3), 204-247; doi:10.3390/cells1030204
Received: 16 May 2012; in revised form: 13 June 2012 / Accepted: 14 June 2012 / Published: 25 June 2012
Show/Hide Abstract | Download PDF Full-text (709 KB) | Download XML Full-text

Cells 2012, 1(2), 168-203; doi:10.3390/cells1020168
Received: 10 May 2012; in revised form: 3 June 2012 / Accepted: 12 June 2012 / Published: 20 June 2012
Show/Hide Abstract | Download PDF Full-text (590 KB) | Download XML Full-text

Last update: 17 April 2014

Cells EISSN 2073-4409 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert