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How Human Tumor Viruses Make Use of Autophagy
AbstractViruses commandeer regulatory pathways of their hosts to optimize their success as cellular parasites. The human tumor viruses, Epstein-Barr Virus (EBV), Kaposi’s Sarcoma Herpesvirus (KSHV), Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV) all affect autophagy for their own ends. EBV and KSHV regulate it during latent infections, a phase when no progeny virus is produced, while HBV and HCV use autophagy to promote their productive infections. Here we shall compare and contrast how these human tumor viruses regulate autophagy and what they gain by the appropriation of this cellular pathway.
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Pratt, Z.L.; Sugden, B. How Human Tumor Viruses Make Use of Autophagy. Cells 2012, 1, 617-630.View more citation formats
Pratt ZL, Sugden B. How Human Tumor Viruses Make Use of Autophagy. Cells. 2012; 1(3):617-630.Chicago/Turabian Style
Pratt, Zachary L.; Sugden, Bill. 2012. "How Human Tumor Viruses Make Use of Autophagy." Cells 1, no. 3: 617-630.