Cells 2012, 1(2), 168-203; doi:10.3390/cells1020168
Review

Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins

Received: 10 May 2012; in revised form: 3 June 2012 / Accepted: 12 June 2012 / Published: 20 June 2012
(This article belongs to the Special Issue Autophagy)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Macroautophagy has important physiological roles and its cytoprotective or detrimental function is compromised in various diseases such as many cancers and metabolic diseases. However, the importance of autophagy for cell responses has also been demonstrated in many other physiological and pathological situations. In this review, we discuss some of the recently discovered mechanisms involved in specific and unspecific autophagy related to mitochondrial dysfunction and organelle degradation, lipid metabolism and lipophagy as well as recent findings and evidence that link autophagy to unconventional protein secretion.
Keywords: mitophagy; lipophagy; specific autophagy; organelle dysfunction; triglyceride accumulation; protein secretion
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MDPI and ACS Style

Demine, S.; Michel, S.; Vannuvel, K.; Wanet, A.; Renard, P.; Arnould, T. Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins. Cells 2012, 1, 168-203.

AMA Style

Demine S, Michel S, Vannuvel K, Wanet A, Renard P, Arnould T. Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins. Cells. 2012; 1(2):168-203.

Chicago/Turabian Style

Demine, Stéphane; Michel, Sébastien; Vannuvel, Kayleen; Wanet, Anaïs; Renard, Patricia; Arnould, Thierry. 2012. "Macroautophagy and Cell Responses Related to Mitochondrial Dysfunction, Lipid Metabolism and Unconventional Secretion of Proteins." Cells 1, no. 2: 168-203.

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