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Modulation of Autophagy-Like Processes by Tumor Viruses
AbstractAutophagy is an intracellular degradation pathway for long-lived proteins and organelles. This process is activated above basal levels upon cell intrinsic or environmental stress and dysregulation of autophagy has been linked to various human diseases, including those caused by viral infection. Many viruses have evolved strategies to directly interfere with autophagy, presumably to facilitate their replication or to escape immune detection. However, in some cases, modulation of autophagy appears to be a consequence of the virus disturbing the cell’s metabolic signaling networks. Here, we summarize recent advances in research at the interface of autophagy and viral infection, paying special attention to strategies that human tumor viruses have evolved.
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Mack, H.I.D.; Munger, K. Modulation of Autophagy-Like Processes by Tumor Viruses. Cells 2012, 1, 204-247.View more citation formats
Mack HID, Munger K. Modulation of Autophagy-Like Processes by Tumor Viruses. Cells. 2012; 1(3):204-247.Chicago/Turabian Style
Mack, Hildegard I. D.; Munger, Karl. 2012. "Modulation of Autophagy-Like Processes by Tumor Viruses." Cells 1, no. 3: 204-247.